Death-Associated Protein Kinase 1 Phosphorylation in Neuronal Cell Death and Neurodegenerative Disease

by Nami Kim, Dongmei Chen, Xiao Zhen Zhou, Tae Ho Lee
Published 2019-06-01

The Rab2A GTPase Promotes Breast Cancer Stem Cells and Tumorigenesis via Erk Signaling Activation

by Man-Li Luo, Chang Gong, Chun-Hau Chen, Hai Hu, Pengyu Huang, Min Zheng, Yandan Yao, Shuo Wei, Gerburg Wulf, Judy Lieberman, Xiao Zhen Zhou, Erwei Song, Kun Ping Lu
Published 2015-04-01

G Protein-coupled Receptor Kinase 2 (GRK2) Promotes Breast Tumorigenesis Through a HDAC6-Pin1 Axis

by Laura Nogués, Clara Reglero, Verónica Rivas, Alicia Salcedo, Vanesa Lafarga, Maria Neves, Paula Ramos, Marta Mendiola, Alberto Berjón, Kostas Stamatakis, Xiao Zhen Zhou, Kun Ping Lu, David Hardisson, Federico Mayor Jr., Petronila Penela
Published 2016-11-01

Prolyl Isomerase Pin1 Regulates Axon Guidance by Stabilizing CRMP2A Selectively in Distal Axons

by Martin Balastik, Xiao Zhen Zhou, Meritxell Alberich-Jorda, Romana Weissova, Jakub Žiak, Maria F. Pazyra-Murphy, Katharina E. Cosker, Olga Machonova, Iryna Kozmikova, Chun-Hau Chen, Lucia Pastorino, John M. Asara, Adam Cole, Calum Sutherland, Rosalind A. Segal, Kun Ping Lu
Published 2015-10-01

The IL-33-PIN1-IRAK-M axis is critical for type 2 immunity in IL-33-induced allergic airway inflammation

by Morris Nechama, Jeahoo Kwon, Shuo Wei, Adrian Tun Kyi, Robert S. Welner, Iddo Z. Ben-Dov, Mohamed S. Arredouani, John M. Asara, Chun-Hau Chen, Cheng-Yu Tsai, Kyle F. Nelson, Koichi S Kobayashi, Elliot Israel, Xiao Zhen Zhou, Linda K. Nicholson, Kun Ping Lu
Published 2018-04-01

Targeting Pin1 by All-Trans Retinoic Acid (ATRA) Overcomes Tamoxifen Resistance in Breast Cancer via Multifactorial Mechanisms

by Songyin Huang, Yang Chen, Zhi-Mei Liang, Zhi-Mei Liang, Na-Na Li, Na-Na Li, Yujie Liu, Yujie Liu, Yinghua Zhu, Yinghua Zhu, Dingzhun Liao, Xiao Zhen Zhou, Kun Ping Lu, Yandan Yao, Yandan Yao, Man-Li Luo, Man-Li Luo
Published 2019-12-01

Arsenic targets Pin1 and cooperates with retinoic acid to inhibit cancer-driving pathways and tumor-initiating cells

by Shingo Kozono, Yu-Min Lin, Hyuk-Soo Seo, Benika Pinch, Xiaolan Lian, Chenxi Qiu, Megan K. Herbert, Chun-Hau Chen, Li Tan, Ziang Jeff Gao, Walter Massefski, Zainab M. Doctor, Brian P. Jackson, Yuanzhong Chen, Sirano Dhe-Paganon, Kun Ping Lu, Xiao Zhen Zhou
Published 2018-08-01

Pin1 cysteine-113 oxidation inhibits its catalytic activity and cellular function in Alzheimer's disease

by Chun-Hau Chen, Wenzong Li, Rukhsana Sultana, Mi-Hyeon You, Asami Kondo, Koorosh Shahpasand, Byeong Mo Kim, Man-Li Luo, Morris Nechama, Yu-Min Lin, Yandan Yao, Tae Ho Lee, Xiao Zhen Zhou, Aaron M. Swomley, D. Allan Butterfield, Yan Zhang, Kun Ping Lu
Published 2015-04-01

Cis P-tau is induced in clinical and preclinical brain injury and contributes to post-injury sequelae

by Onder Albayram, Asami Kondo, Rebekah Mannix, Colin Smith, Cheng-Yu Tsai, Chenyu Li, Megan K. Herbert, Jianhua Qiu, Michael Monuteaux, Jane Driver, Sandra Yan, William Gormley, Ava M. Puccio, David O. Okonkwo, Brandon Lucke-Wold, Julian Bailes, William Meehan, Mark Zeidel, Kun Ping Lu, Xiao Zhen Zhou
Published 2017-10-01

Correction to: Pin1 inhibition exerts potent activity against acute myeloid leukemia through blocking multiple cancer-driving pathways

by Xiaolan Lian, Yu-Min Lin, Shingo Kozono, Megan K. Herbert, Xin Li, Xiaohong Yuan, Jiangrui Guo, Yafei Guo, Min Tang, Jia Lin, Yiping Huang, Bixin Wang, Chenxi Qiu, Cheng-Yu Tsai, Jane Xie, Ziang Jeff Gao, Yong Wu, Hekun Liu, Xiao Zhen Zhou, Kun Ping Lu, Yuanzhong Chen
Published 2018-07-01

Pin1 inhibition exerts potent activity against acute myeloid leukemia through blocking multiple cancer-driving pathways

by Xiaolan Lian, Yu-Min Lin, Shingo Kozono, Megan K. Herbert, Xin Li, Xiaohong Yuan, Jiangrui Guo, Yafei Guo, Min Tang, Jia Lin, Yiping Huang, Bixin Wang, Chenxi Qiu, Cheng-Yu Tsai, Jane Xie, Ziang Jeff Gao, Yong Wu, Hekun Liu, Xiao Zhen Zhou, Kun Ping Lu, Yuanzhong Chen
Published 2018-05-01