Retinoic acid promotes barrier functions in human iPSC-derived intestinal epithelial monolayers

by Shigeru Yamada, Yasunari Kanda
Published 2019-08-01

A Method of Three-Dimensional Micro-Rotational Flow Generation for Biological Applications

by Yaxiaer Yalikun, Yasunari Kanda, Keisuke Morishima
Published 2016-08-01

Oxidative Stress as a Common Key Event in Developmental Neurotoxicity

by Yuhei Nishimura, Yasunari Kanda, Hideko Sone, Hiroaki Aoyama
Published 2021-01-01

FTY720 Inhibits Expansion of Breast Cancer Stem Cells via PP2A Activation

by Naoya Hirata, Shigeru Yamada, Shota Yanagida, Atsushi Ono, Yasunari Kanda
Published 2021-07-01

Development of torsadogenic risk assessment using human induced pluripotent stem cell-derived cardiomyocytes: Japan iPS Cardiac Safety Assessment (JiCSA) update

by Yasunari Kanda, Daiju Yamazaki, Tomoharu Osada, Takashi Yoshinaga, Kohei Sawada
Published 2018-12-01

Assessment of Testing Methods for Drug-Induced Repolarization Delay and Arrhythmias in an iPS Cell–Derived Cardiomyocyte Sheet: Multi-site Validation Study

by Yuji Nakamura, Junko Matsuo, Norimasa Miyamoto, Atsuko Ojima, Kentaro Ando, Yasunari Kanda, Kohei Sawada, Atsushi Sugiyama, Yuko Sekino
Published 2014-01-01

Application of human induced pluripotent stem cell-derived cardiomyocytes sheets with microelectrode array system to estimate antiarrhythmic properties of multi-ion channel blocker...

by Hiroko Izumi-Nakaseko, Mihoko Hagiwara-Nagasawa, Atsuhiko T. Naito, Ai Goto, Koki Chiba, Yuko Sekino, Yasunari Kanda, Atsushi Sugiyama
Published 2018-08-01

A deep learning algorithm to translate and classify cardiac electrophysiology

by Parya Aghasafari, Pei-Chi Yang, Divya C Kernik, Kazuho Sakamoto, Yasunari Kanda, Junko Kurokawa, Igor Vorobyov, Colleen E Clancy
Published 2021-07-01

Specific induction and long-term maintenance of high purity ventricular cardiomyocytes from human induced pluripotent stem cells.

by Hiroyuki Fukushima, Miki Yoshioka, Masahide Kawatou, Víctor López-Dávila, Masafumi Takeda, Yasunari Kanda, Yuko Sekino, Yoshinori Yoshida, Jun K Yamashita
Published 2020-01-01

Pharmacological β-adrenoceptor blockade can augment torsadogenic action of IKr inhibitor: Comparison of proarrhythmic effects of d-sotalol and dl-sotalol in the chronic atrioventri...

by Ai Goto, Mihoko Hagiwara-Nagasawa, Koki Chiba, Ryuichi Kambayashi, Yoshio Nunoi, Hiroko Izumi-Nakaseko, Akio Matsumoto, Yasunari Kanda, Atsushi Sugiyama
Published 2019-09-01

Analysis of electro-mechanical relationship in human iPS cell-derived cardiomyocytes sheets under proarrhythmic condition assessed by simultaneous field potential and motion vector...

by Atsushi Sugiyama, Mihoko Hagiwara-Nagasawa, Ryuichi Kambayashi, Ai Goto, Koki Chiba, Atsuhiko T. Naito, Yasunari Kanda, Akio Matsumoto, Hiroko Izumi-Nakaseko
Published 2019-08-01

Development of correction formula for field potential duration of human induced pluripotent stem cell-derived cardiomyocytes sheets

by Hiroko Izumi-Nakaseko, Yasunari Kanda, Yuji Nakamura, Mihoko Hagiwara-Nagasawa, Takeshi Wada, Kentaro Ando, Atsuhiko T. Naito, Yuko Sekino, Atsushi Sugiyama
Published 2017-09-01

Low-Concentration Tributyltin Decreases GluR2 Expression via Nuclear Respiratory Factor-1 Inhibition

by Keishi Ishida, Kaori Aoki, Tomoko Takishita, Masatsugu Miyara, Shuichiro Sakamoto, Seigo Sanoh, Tomoki Kimura, Yasunari Kanda, Shigeru Ohta, Yaichiro Kotake
Published 2017-08-01

Overexpression of KCNJ2 in induced pluripotent stem cell-derived cardiomyocytes for the assessment of QT-prolonging drugs

by Min Li, Yasunari Kanda, Takashi Ashihara, Tetsuo Sasano, Yuji Nakai, Masami Kodama, Erina Hayashi, Yuko Sekino, Tetsushi Furukawa, Junko Kurokawa
Published 2017-06-01

Highly sensitive in vitro methods for detection of residual undifferentiated cells in retinal pigment epithelial cells derived from human iPS cells.

by Takuya Kuroda, Satoshi Yasuda, Shinji Kusakawa, Naoya Hirata, Yasunari Kanda, Kazuhiro Suzuki, Masayo Takahashi, Shin-Ichi Nishikawa, Shin Kawamata, Yoji Sato
Published 2012-01-01

Systematic expression analysis of genes related to generation of action potentials in human iPS cell-derived cardiomyocytes

by Masami Kodama, Kazuharu Furutani, Reiko Kimura, Tomoko Ando, Kazuho Sakamoto, Shushi Nagamori, Takashi Ashihara, Yoshihisa Kurachi, Yuko Sekino, Tetsushi Furukawa, Yasunari Kanda, Junko Kurokawa
Published 2019-08-01

‘All In’: a pragmatic framework for COVID‐19 testing and action on a global scale

by Syril D Pettit, Keith R Jerome, David Rouquié, Bernard Mari, Pascal Barbry, Yasunari Kanda, Mineo Matsumoto, Susan Hester, Leah Wehmas, Jason W Botten, Emily A Bruce
Published 2020-06-01

Optimizing the Direction and Order of the Motion Unveiled the Ability of Conventional Monolayers of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes to Show Frequency-Dep...

by Hiroko Izumi-Nakaseko, Koki Chiba, Mihoko Hagiwara-Nagasawa, Ayano Satsuka, Ai Goto, Yoshio Nunoi, Ryuichi Kambayashi, Akio Matsumoto, Yoshinori Takei, Yasunari Kanda, Atsuhiko T. Naito, Atsushi Sugiyama, Atsushi Sugiyama, Atsushi Sugiyama
Published 2020-09-01

Proarrhythmia risk prediction using human induced pluripotent stem cell-derived cardiomyocytes

by Daiju Yamazaki, Takashi Kitaguchi, Masakazu Ishimura, Tomohiko Taniguchi, Atsuhiro Yamanishi, Daisuke Saji, Etsushi Takahashi, Masao Oguchi, Yuta Moriyama, Sanae Maeda, Kaori Miyamoto, Kaoru Morimura, Hiroki Ohnaka, Hiroyuki Tashibu, Yuko Sekino, Norimasa Miyamoto, Yasunari Kanda
Published 2018-04-01

Electrophysiological Characteristics of Human iPSC-Derived Cardiomyocytes for the Assessment of Drug-Induced Proarrhythmic Potential.

by Wataru Yamamoto, Keiichi Asakura, Hiroyuki Ando, Tomohiko Taniguchi, Atsuko Ojima, Takaaki Uda, Tomoharu Osada, Seiji Hayashi, Chieko Kasai, Norimasa Miyamoto, Hiroyuki Tashibu, Takashi Yoshinaga, Daiju Yamazaki, Atsushi Sugiyama, Yasunari Kanda, Kohei Sawada, Yuko Sekino
Published 2016-01-01