Identification of potential small molecule allosteric modulator sites on IL-1R1 ectodomain using accelerated conformational sampling method.

by Chao-Yie Yang
Published 2015-01-01

Enrichment of Druggable Conformations from Apo Protein Structures Using Cosolvent-Accelerated Molecular Dynamics

by Andrew Kalenkiewicz, Barry J. Grant, Chao-Yie Yang
Published 2015-04-01

Synaptotagmin 7 in twist-related protein 1-mediated epithelial – Mesenchymal transition of non-small cell lung cancerResearch in context

by Xiao Liu, Chunyu Li, Yie Yang, Xiaoxia Liu, Rui Li, Mengyu Zhang, Yunhong Yin, Yiqing Qu
Published 2019-08-01

Conformational Sampling and Binding Site Assessment of Suppression of Tumorigenicity 2 Ectodomain.

by Chao-Yie Yang, James Delproposto, Krishnapriya Chinnaswamy, William Clay Brown, Shuying Wang, Jeanne A Stuckey, Xinquan Wang
Published 2016-01-01

Significant Differences in the Development of Acquired Resistance to the MDM2 Inhibitor SAR405838 between In Vitro and In Vivo Drug Treatment.

by C Gianna Hoffman-Luca, Chao-Yie Yang, Jianfeng Lu, Daniel Ziazadeh, Donna McEachern, Laurent Debussche, Shaomeng Wang
Published 2015-01-01

Selective inhibition of cullin 3 neddylation through covalent targeting DCN1 protects mice from acetaminophen-induced liver toxicity

by Haibin Zhou, Jianfeng Lu, Krishnapriya Chinnaswamy, Jeanne A. Stuckey, Liu Liu, Donna McEachern, Chao-Yie Yang, Denzil Bernard, Hong Shen, Liangyou Rui, Yi Sun, Shaomeng Wang
Published 2021-05-01

A potent small-molecule inhibitor of the DCN1-UBC12 interaction that selectively blocks cullin 3 neddylation

by Haibin Zhou, Jianfeng Lu, Liu Liu, Denzil Bernard, Chao-Yie Yang, Ester Fernandez-Salas, Krishnapriya Chinnaswamy, Stephanie Layton, Jeanne Stuckey, Qing Yu, Weihua Zhou, Zhenqiang Pan, Yi Sun, Shaomeng Wang
Published 2017-10-01