A Novel Strategy for Inducing the Antitumor Effects of Triterpenoid Compounds: Blocking the Protumoral Functions of Tumor-Associated Macrophages via STAT3 Inhibition

by Yukio Fujiwara, Motohiro Takeya, Yoshihiro Komohara
Published 2014-01-01

Alginates as food ingredients absorb extra salt in sodium chloride-treated mice

by Yukio Fujiwara, Ryoko Maeda, Hidenori Takeshita, Yoshihiro Komohara
Published 2021-03-01

CD169 Expression on Lymph Node Macrophages Predicts in Patients With Gastric Cancer

by Keiichiro Kumamoto, Keiichiro Kumamoto, Takashi Tasaki, Takashi Tasaki, Koji Ohnishi, Michihiko Shibata, Shohei Shimajiri, Masaru Harada, Yoshihiro Komohara, Yoshihiro Komohara, Toshiyuki Nakayama
Published 2021-03-01

Culture System for a Closer Biological Contact Between Macrophages and Microparticles

by Haruki Miyamoto, Katsunori Higuchi, Yuta Nakashima, Yukio Fujiwara, Yoshihiro Komohara, Yoshitaka Nakanishi
Published 2021-02-01

Anti-Cancer Immune Reaction and Lymph Node Macrophage; A Review from Human and Animal Studies

by Yoshihiro Komohara, Toshiki Anami, Kenichi Asano, Yukio Fujiwara, Junji Yatsuda, Tomomi Kamba
Published 2021-07-01

Platelet-Like Gold Nanostars for Cancer Therapy: The Ability to Treat Cancer and Evade Immune Reactions

by Min Woo Kim, Gibok Lee, Takuro Niidome, Yoshihiro Komohara, Ruda Lee, Yong Il Park
Published 2020-02-01

Soyasapogenols contained in soybeans suppress tumour progression by regulating macrophage differentiation into the protumoural phenotype

by Yukio Fujiwara, Daisuke Shiraishi, Makiko Yoshitomi, Tsuyoshi Ikeda, Hiroshi Mizuta, Motohiro Takeya, Yoshihiro Komohara
Published 2015-12-01

DPP-4 inhibition with linagliptin ameliorates the progression of premature aging in klotho−/− mice

by Yu Hasegawa, Kenyu Hayashi, Yushin Takemoto, Cao Cheng, Koki Takane, Bowen Lin, Yoshihiro Komohara, Shokei Kim-Mitsuyama
Published 2017-12-01

The Clinical Significance of CD169-Positive Lymph Node Macrophage in Patients with Breast Cancer.

by Takuya Shiota, Yuko Miyasato, Koji Ohnishi, Mutsuko Yamamoto-Ibusuki, Yutaka Yamamoto, Hirotaka Iwase, Motohiro Takeya, Yoshihiro Komohara
Published 2016-01-01

Identification of miR-30e* regulation of Bmi1 expression mediated by tumor-associated macrophages in gastrointestinal cancer.

by Hidetaka Sugihara, Takatsugu Ishimoto, Masayuki Watanabe, Hiroshi Sawayama, Masaaki Iwatsuki, Yoshifumi Baba, Yoshihiro Komohara, Motohiro Takeya, Hideo Baba
Published 2013-01-01

Oligodendrocyte Progenitor Cells and Macrophages/Microglia Produce Glioma Stem Cell Niches at the Tumor Border

by Takuichiro Hide, Yoshihiro Komohara, Yuko Miyasato, Hideo Nakamura, Keishi Makino, Motohiro Takeya, Jun-ichi Kuratsu, Akitake Mukasa, Shigetoshi Yano
Published 2018-04-01

CD163 deficiency facilitates lipopolysaccharide‐induced inflammatory responses and endotoxin shock in mice

by Yukio Fujiwara, Koji Ohnishi, Hasita Horlad, Yoichi Saito, Daisuke Shiraishi, Hiroto Takeya, Daiki Yoshii, Shinjiro Kaieda, Tomoaki Hoshino, Yoshihiro Komohara
Published 2020-01-01

Relationship between wear behaviour of ultra-high-molecular-weight polyethylene and surface profile of Co–Cr–Mo alloy in artificial joint

by Nana Motojima, Yuta Nakashima, Yukio Fujiwara, Yoshihiro Komohara, Motohiro Takeya, Hiromasa Miura, Kazunori Hino, Hidehiko Higaki, Hidehiro Hata, Yoshitaka Nakanishi
Published 2019-01-01

Remarkable antitumor effect of nivolumab in a patient with metastatic renal cell carcinoma previously treated with a peptide‐based vaccine

by Ryoma Kurahashi, Takanobu Motoshima, Yumi Fukushima, Yoji Murakami, Junji Yatsuda, Takahiro Yamaguchi, Yutaka Sugiyama, Satoshi Fukushima, Yoshihiro Komohara, Shigetaka Suekane, Tomomi Kamba
Published 2020-03-01

Overexpression of CD163, CD204 and CD206 on alveolar macrophages in the lungs of patients with severe chronic obstructive pulmonary disease.

by Yoichiro Kaku, Haruki Imaoka, Yoshitaka Morimatsu, Yoshihiro Komohara, Koji Ohnishi, Hanako Oda, Shinichi Takenaka, Masanobu Matsuoka, Tomotaka Kawayama, Motohiro Takeya, Tomoaki Hoshino
Published 2014-01-01

Flavonoid Compounds Contained in Epimedii Herba Inhibit Tumor Progression by Suppressing STAT3 Activation in the Tumor Microenvironment

by Cheng Pan, Yukio Fujiwara, Hasita Horlad, Daisuke Shiraishi, Daisuke Shiraishi, Toyohisa Iriki, Toyohisa Iriki, Jyunko Tsuboki, Jyunko Tsuboki, Tsuyoshi Ikeda, Yoshihiro Komohara
Published 2020-03-01

Colonization of distant organs by tumor cells generating circulating homotypic clusters adaptive to fluid shear stress

by Manabu Maeshiro, Satoru Shinriki, Rin Liu, Yutaka Nakachi, Yoshihiro Komohara, Yukio Fujiwara, Kazuaki Ohtsubo, Ryoji Yoshida, Kazuya Iwamoto, Hideki Nakayama, Hirotaka Matsui
Published 2021-03-01

Involvement of Macrophages in the Pathogenesis of Familial Amyloid Polyneuropathy and Efficacy of Human iPS Cell-Derived Macrophages in Its Treatment.

by Genki Suenaga, Tokunori Ikeda, Yoshihiro Komohara, Koutaro Takamatsu, Tatsuyuki Kakuma, Masayoshi Tasaki, Yohei Misumi, Mitsuharu Ueda, Takaaki Ito, Satoru Senju, Yukio Ando
Published 2016-01-01

The imaging findings of Peliosis hepatis on gadoxetic acid enhanced MRI

by Morikatsu Yoshida, MD, Daisuke Utsunomiya, MD, Sentaro Takada, MD, Yoshihiro Komohara, MD, Tomohiro Mizoshiri, MD, Seitaro Oda, MD, Kazunori Harada, MD, Osamu Ikeda, MD
Published 2020-08-01

Mtu1-Mediated Thiouridine Formation of Mitochondrial tRNAs Is Required for Mitochondrial Translation and Is Involved in Reversible Infantile Liver Injury.

by Yong Wu, Fan-Yan Wei, Layla Kawarada, Takeo Suzuki, Kimi Araki, Yoshihiro Komohara, Atsushi Fujimura, Taku Kaitsuka, Motohiro Takeya, Yuichi Oike, Tsutomu Suzuki, Kazuhito Tomizawa
Published 2016-09-01