Comparative Description of the Expression Profile of Interferon-Stimulated Genes in Multiple Cell Lineages Targeted by HIV-1 Infection

by Hirofumi Aso, Hirofumi Aso, Jumpei Ito, Yoshio Koyanagi, Yoshio Koyanagi, Kei Sato, Kei Sato
Published 2019-03-01

Impacts of Humanized Mouse Models on the Investigation of HIV-1 Infection: Illuminating the Roles of Viral Accessory Proteins in Vivo

by Eri Yamada, Rokusuke Yoshikawa, Yusuke Nakano, Naoko Misawa, Yoshio Koyanagi, Kei Sato
Published 2015-03-01

M-Sec facilitates intercellular transmission of HIV-1 through multiple mechanisms

by Sameh Lotfi, Hesham Nasser, Osamu Noyori, Masateru Hiyoshi, Hiroaki Takeuchi, Yoshio Koyanagi, Shinya Suzu
Published 2020-07-01

A high excision potential of TALENs for integrated DNA of HIV-based lentiviral vector.

by Hirotaka Ebina, Yuka Kanemura, Naoko Misawa, Tetsushi Sakuma, Tomoko Kobayashi, Takashi Yamamoto, Yoshio Koyanagi
Published 2015-01-01

A conflict of interest: the evolutionary arms race between mammalian APOBEC3 and lentiviral Vif

by Yusuke Nakano, Hirofumi Aso, Andrew Soper, Eri Yamada, Miyu Moriwaki, Guillermo Juarez-Fernandez, Yoshio Koyanagi, Kei Sato
Published 2017-05-01

HIV-1 Vpr accelerates viral replication during acute infection by exploitation of proliferating CD4+ T cells in vivo.

by Kei Sato, Naoko Misawa, Shingo Iwami, Yorifumi Satou, Masao Matsuoka, Yukihito Ishizaka, Mamoru Ito, Kazuyuki Aihara, Dong Sung An, Yoshio Koyanagi
Published 2013-01-01

SARS-CoV-2 ORF3b Is a Potent Interferon Antagonist Whose Activity Is Increased by a Naturally Occurring Elongation Variant

by Yoriyuki Konno, Izumi Kimura, Keiya Uriu, Masaya Fukushi, Takashi Irie, Yoshio Koyanagi, Daniel Sauter, Robert J. Gifford, So Nakagawa, Kei Sato
Published 2020-09-01

Cell-to-cell infection by HIV contributes over half of virus infection

by Shingo Iwami, Junko S Takeuchi, Shinji Nakaoka, Fabrizio Mammano, François Clavel, Hisashi Inaba, Tomoko Kobayashi, Naoko Misawa, Kazuyuki Aihara, Yoshio Koyanagi, Kei Sato
Published 2015-10-01

New World feline APOBEC3 potently controls inter-genus lentiviral transmission

by Yoriyuki Konno, Shumpei Nagaoka, Izumi Kimura, Keisuke Yamamoto, Yumiko Kagawa, Ryuichi Kumata, Hirofumi Aso, Mahoko Takahashi Ueda, So Nakagawa, Tomoko Kobayashi, Yoshio Koyanagi, Kei Sato
Published 2018-04-01

Type I Interferon Responses by HIV-1 Infection: Association with Disease Progression and Control

by Andrew Soper, Andrew Soper, Izumi Kimura, Izumi Kimura, Shumpei Nagaoka, Shumpei Nagaoka, Yoriyuki Konno, Yoriyuki Konno, Keisuke Yamamoto, Keisuke Yamamoto, Yoshio Koyanagi, Kei Sato, Kei Sato
Published 2018-01-01

Dynamics and mechanisms of clonal expansion of HIV-1-infected cells in a humanized mouse model

by Yorifumi Satou, Hiroo Katsuya, Asami Fukuda, Naoko Misawa, Jumpei Ito, Yoshikazu Uchiyama, Paola Miyazato, Saiful Islam, Ariberto Fassati, Anat Melamed, Charles R. M. Bangham, Yoshio Koyanagi, Kei Sato
Published 2017-07-01

Multiomics Investigation Revealing the Characteristics of HIV-1-Infected Cells In Vivo

by Hirofumi Aso, Shumpei Nagaoka, Eiryo Kawakami, Jumpei Ito, Saiful Islam, Benjy Jek Yang Tan, Shinji Nakaoka, Koichi Ashizaki, Katsuyuki Shiroguchi, Yutaka Suzuki, Yorifumi Satou, Yoshio Koyanagi, Kei Sato
Published 2020-07-01

CKIP-1 is an intrinsic negative regulator of T-cell activation through an interaction with CARMA1.

by Takashi Sakamoto, Masayuki Kobayashi, Kohei Tada, Masanobu Shinohara, Katsuhiro Io, Kayoko Nagata, Fumie Iwai, Yoko Takiuchi, Yasuyuki Arai, Kouhei Yamashita, Keisuke Shindo, Norimitsu Kadowaki, Yoshio Koyanagi, Akifumi Takaori-Kondo
Published 2014-01-01

HIV-1 competition experiments in humanized mice show that APOBEC3H imposes selective pressure and promotes virus adaptation.

by Yusuke Nakano, Naoko Misawa, Guillermo Juarez-Fernandez, Miyu Moriwaki, Shinji Nakaoka, Takaaki Funo, Eri Yamada, Andrew Soper, Rokusuke Yoshikawa, Diako Ebrahimi, Yuuya Tachiki, Shingo Iwami, Reuben S Harris, Yoshio Koyanagi, Kei Sato
Published 2017-05-01

APOBEC3D and APOBEC3F potently promote HIV-1 diversification and evolution in humanized mouse model.

by Kei Sato, Junko S Takeuchi, Naoko Misawa, Taisuke Izumi, Tomoko Kobayashi, Yuichi Kimura, Shingo Iwami, Akifumi Takaori-Kondo, Wei-Shau Hu, Kazuyuki Aihara, Mamoru Ito, Dong Sung An, Vinay K Pathak, Yoshio Koyanagi
Published 2014-10-01

Host factor SAMHD1 restricts DNA viruses in non-dividing myeloid cells.

by Joseph A Hollenbaugh, Peter Gee, Jonathon Baker, Jonathon Baker, Michele B Daly, Sarah M Amie, Jessica Tate, Natsumi Kasai, Yuka Kanemura, Dong-Hyun Kim, Brian M Ward, Yoshio Koyanagi, Baek Kim
Published 2013-01-01

Correction: HIV-1 competition experiments in humanized mice show that APOBEC3H imposes selective pressure and promotes virus adaptation.

by Yusuke Nakano, Naoko Misawa, Guillermo Juarez-Fernandez, Miyu Moriwaki, Shinji Nakaoka, Takaaki Funo, Eri Yamada, Andrew Soper, Rokusuke Yoshikawa, Diako Ebrahimi, Yuuya Tachiki, Shingo Iwami, Reuben S Harris, Yoshio Koyanagi, Kei Sato
Published 2017-09-01

A novel protective MHC-I haplotype not associated with dominant Gag-specific CD8+ T-cell responses in SIVmac239 infection of Burmese rhesus macaques.

by Naofumi Takahashi, Takushi Nomura, Yusuke Takahara, Hiroyuki Yamamoto, Teiichiro Shiino, Akiko Takeda, Makoto Inoue, Akihiro Iida, Hiroto Hara, Tsugumine Shu, Mamoru Hasegawa, Hiromi Sakawaki, Tomoyuki Miura, Tatsuhiko Igarashi, Yoshio Koyanagi, Taeko K Naruse, Akinori Kimura, Tetsuro Matano
Published 2013-01-01

Lack of association between intact/deletion polymorphisms of the APOBEC3B gene and HIV-1 risk.

by Mayumi Imahashi, Taisuke Izumi, Dai Watanabe, Junji Imamura, Kazuhiro Matsuoka, Hirotaka Ode, Takashi Masaoka, Kei Sato, Noriyo Kaneko, Seiichi Ichikawa, Yoshio Koyanagi, Akifumi Takaori-Kondo, Makoto Utsumi, Yoshiyuki Yokomaku, Takuma Shirasaka, Wataru Sugiura, Yasumasa Iwatani, Tomoki Naoe
Published 2014-01-01

A role for gorilla APOBEC3G in shaping lentivirus evolution including transmission to humans.

by Yusuke Nakano, Keisuke Yamamoto, Mahoko Takahashi Ueda, Andrew Soper, Yoriyuki Konno, Izumi Kimura, Keiya Uriu, Ryuichi Kumata, Hirofumi Aso, Naoko Misawa, Shumpei Nagaoka, Soma Shimizu, Keito Mitsumune, Yusuke Kosugi, Guillermo Juarez-Fernandez, Jumpei Ito, So Nakagawa, Terumasa Ikeda, Yoshio Koyanagi, Reuben S Harris, Kei Sato
Published 2020-09-01