Editorial for the Special Issue “Animal Models of Parkinson’s Disease and Related Disorders”

by Yuzuru Imai
Published 2020-06-01

Regulation of vesicular trafficking by Parkinson's disease-associated genes

by Tsuyoshi Inoshita, Yuzuru Imai
Published 2015-10-01

Editorial: Molecular Links Between Mitochondrial Damage and Parkinson's Disease and Related Disorders

by Yuzuru Imai, Yuzuru Imai, Kiyoung Kim, Kiyoung Kim, Zhihao Wu, Shigeto Sato
Published 2021-08-01

Lipids: Key Players That Modulate α-Synuclein Toxicity and Neurodegeneration in Parkinson’s Disease

by Akio Mori, Yuzuru Imai, Nobutaka Hattori
Published 2020-05-01

Animal Models of Parkinson's Disease 2012

by Yuzuru Imai, Katerina Venderova, Kah-Leong Lim
Published 2012-01-01

Twin CHCH Proteins, CHCHD2, and CHCHD10: Key Molecules of Parkinson’s Disease, Amyotrophic Lateral Sclerosis, and Frontotemporal Dementia

by Yuzuru Imai, Hongrui Meng, Kahori Shiba-Fukushima, Nobutaka Hattori
Published 2019-02-01

PINK1-mediated phosphorylation of Parkin boosts Parkin activity in Drosophila.

by Kahori Shiba-Fukushima, Tsuyoshi Inoshita, Nobutaka Hattori, Yuzuru Imai
Published 2014-06-01

Animal Models of Parkinson's Disease

by Yuzuru Imai, Katerina Venderova, David S. Park, Huaibin Cai, Enrico Schmidt
Published 2011-01-01

Reduced TDP-43 Expression Improves Neuronal Activities in a Drosophila Model of Perry Syndrome

by Yuka Hosaka, Tsuyoshi Inoshita, Kahori Shiba-Fukushima, Changxu Cui, Taku Arano, Yuzuru Imai, Nobutaka Hattori
Published 2017-07-01

The nitric oxide-cyclic GMP pathway regulates FoxO and alters dopaminergic neuron survival in Drosophila.

by Tomoko Kanao, Tomoyo Sawada, Shireen-Anne Davies, Hiroshi Ichinose, Kazuko Hasegawa, Ryosuke Takahashi, Nobutaka Hattori, Yuzuru Imai
Published 2012-01-01

A Novel LRRK2 Variant p.G2294R in the WD40 Domain Identified in Familial Parkinson’s Disease Affects LRRK2 Protein Levels

by Jun Ogata, Kentaro Hirao, Kenya Nishioka, Arisa Hayashida, Yuanzhe Li, Hiroyo Yoshino, Soichiro Shimizu, Nobutaka Hattori, Yuzuru Imai
Published 2021-04-01

A Cell-Based High-Throughput Screening Identified Two Compounds that Enhance PINK1-Parkin Signaling

by Kahori Shiba-Fukushima, Tsuyoshi Inoshita, Osamu Sano, Hidehisa Iwata, Kei-ichi Ishikawa, Hideyuki Okano, Wado Akamatsu, Yuzuru Imai, Nobutaka Hattori
Published 2020-05-01

The loss of PGAM5 suppresses the mitochondrial degeneration caused by inactivation of PINK1 in Drosophila.

by Yuzuru Imai, Tomoko Kanao, Tomoyo Sawada, Yoshito Kobayashi, Yasuhiro Moriwaki, Yosuke Ishida, Kohsuke Takeda, Hidenori Ichijo, Bingwei Lu, Ryosuke Takahashi
Published 2010-12-01

Phosphorylation of mitochondrial polyubiquitin by PINK1 promotes Parkin mitochondrial tethering.

by Kahori Shiba-Fukushima, Taku Arano, Gen Matsumoto, Tsuyoshi Inoshita, Shigeharu Yoshida, Yasushi Ishihama, Kwon-Yul Ryu, Nobuyuki Nukina, Nobutaka Hattori, Yuzuru Imai
Published 2014-12-01

Loss of Parkinson’s disease-associated protein CHCHD2 affects mitochondrial crista structure and destabilizes cytochrome c

by Hongrui Meng, Chikara Yamashita, Kahori Shiba-Fukushima, Tsuyoshi Inoshita, Manabu Funayama, Shigeto Sato, Tomohisa Hatta, Tohru Natsume, Masataka Umitsu, Junichi Takagi, Yuzuru Imai, Nobutaka Hattori
Published 2017-06-01

Parkinson's disease-associated kinase PINK1 regulates Miro protein level and axonal transport of mitochondria.

by Song Liu, Tomoyo Sawada, Seongsoo Lee, Wendou Yu, George Silverio, Philomena Alapatt, Ivan Millan, Alice Shen, William Saxton, Tomoko Kanao, Ryosuke Takahashi, Nobutaka Hattori, Yuzuru Imai, Bingwei Lu
Published 2012-01-01

The Parkinson's Disease-Associated Protein Kinase LRRK2 Modulates Notch Signaling through the Endosomal Pathway.

by Yuzuru Imai, Yoshito Kobayashi, Tsuyoshi Inoshita, Hongrui Meng, Taku Arano, Kengo Uemura, Takeshi Asano, Kenji Yoshimi, Chang-Liang Zhang, Gen Matsumoto, Toshiyuki Ohtsuka, Ryoichiro Kageyama, Hiroshi Kiyonari, Go Shioi, Nobuyuki Nukina, Nobutaka Hattori, Ryosuke Takahashi
Published 2015-09-01

Quantitative Assessment of Eye Phenotypes for Functional Genetic Studies Using Drosophila melanogaster

by Janani Iyer, Qingyu Wang, Thanh Le, Lucilla Pizzo, Sebastian Grönke, Surendra S. Ambegaokar, Yuzuru Imai, Ashutosh Srivastava, Beatriz Llamusí Troisí, Graeme Mardon, Ruben Artero, George R. Jackson, Adrian M. Isaacs, Linda Partridge, Bingwei Lu, Justin P. Kumar, Santhosh Girirajan
Published 2016-05-01

UQCRC1 engages cytochrome c for neuronal apoptotic cell death

by Yu-Chien Hung, Kuan-Lin Huang, Po-Lin Chen, Jeng-Lin Li, Serena Huei-An Lu, Jui-Chih Chang, Han-Yi Lin, Wen-Chun Lo, Shu-Yi Huang, Tai-Ting Lee, Tai-Yi Lin, Yuzuru Imai, Nobutaka Hattori, Chin-San Liu, Su-Yi Tsai, Chun-Hong Chen, Chin-Hsien Lin, Chih-Chiang Chan
Published 2021-09-01

Generation and characterization of novel conformation-specific monoclonal antibodies for α-synuclein pathology

by Nishant N. Vaikath, Nour K. Majbour, Katerina E. Paleologou, Mustafa T. Ardah, Esther van Dam, Wilma D.J. van de Berg, Shelley L. Forrest, Laura Parkkinen, Wei-Ping Gai, Nobutaka Hattori, Masashi Takanashi, Seung-Jae Lee, David M.A. Mann, Yuzuru Imai, Glenda M. Halliday, Jia-Yi. Li, Omar M.A. El-Agnaf
Published 2015-07-01