The role of follicular helper CD4 T cells in the development of HIV-1 specific broadly neutralizing antibody responses

The role of follicular helper CD4 T cells in the development of HIV-1 specific broadly neutralizing antibody responses

Abstract The induction of HIV-1-specific antibodies that can neutralize a broad number of isolates is a major goal of HIV-1 vaccination strategies. However, to date no candidate HIV-1 vaccine has successfully elicited broadly neutralizing antibodies of sufficient quality and breadth for protection....

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Bibliographic Details
Main Authors: Eirini Moysi, Constantinos Petrovas, Richard A. Koup
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Retrovirology
Subjects:
Germinal center
Tfh
Broadly neutralizing antibody
Vaccines
Online Access:http://link.springer.com/article/10.1186/s12977-018-0437-y

Internet

http://link.springer.com/article/10.1186/s12977-018-0437-y

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