Highly Purified versus Filtered Crude Collagenase: Comparable Human Islet Isolation Outcomes

This study was designed to retrospectively compare the impact of crude Sigma V collagenase (Sigma V, n = 52) with high-purified Serva NB1 collagenase (Serva NB1, n = 42) on human islet isolation outcomes. A three-step filtration was applied to the crude Sigma V to remove endotoxin contamination and...

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Bibliographic Details
Main Authors: Yong Wang, Daniel Paushter, Shusen Wang, Barbara Barbaro, Tricia Harvat, Kirstie K. Danielson, Katie Kinzer, Liza Zhang, Meirigeng Qi, Jose Oberholzer
Format: Article
Language:English
Published: SAGE Publishing 2011-12-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368911X564994