Transcriptional profiling of leukocytes in critically ill COVID19 patients: implications for interferon response and coagulation

Transcriptional profiling of leukocytes in critically ill COVID19 patients: implications for interferon response and coagulation

Abstract Background COVID19 is caused by the SARS-CoV-2 virus and has been associated with severe inflammation leading to organ dysfunction and mortality. Our aim was to profile the transcriptome in leukocytes from critically ill patients positive for COVID19 compared to those negative for COVID19 t...

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Bibliographic Details
Main Authors: Sean E. Gill, Claudia C. dos Santos, David B. O’Gorman, David E. Carter, Eric K. Patterson, Marat Slessarev, Claudio Martin, Mark Daley, Michael R. Miller, Gediminas Cepinskas, Douglas D. Fraser, Lawson COVID19 Study Team
Format: Article
Language:English
Published: SpringerOpen 2020-12-01
Series:Intensive Care Medicine Experimental
Subjects:
COVID19
RNAseq
Leukocyte transcriptome
Online Access:https://doi.org/10.1186/s40635-020-00361-9

Internet

https://doi.org/10.1186/s40635-020-00361-9

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