Clinical-grade whole-genome sequencing and 3′ transcriptome analysis of colorectal cancer patients

Clinical-grade whole-genome sequencing and 3′ transcriptome analysis of colorectal cancer patients

Abstract Background Clinical-grade whole-genome sequencing (cWGS) has the potential to become the standard of care within the clinic because of its breadth of coverage and lack of bias towards certain regions of the genome. Colorectal cancer presents a difficult treatment paradigm, with over 40% of...

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Bibliographic Details
Main Authors: Agata Stodolna, Miao He, Mahesh Vasipalli, Zoya Kingsbury, Jennifer Becq, Joanne D. Stockton, Mark P. Dilworth, Jonathan James, Toju Sillo, Daniel Blakeway, Stephen T. Ward, Tariq Ismail, Mark T. Ross, Andrew D. Beggs
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Genome Medicine
Subjects:
Pathological complete response
Chemoradiotherapy
Rectal cancer
Genomics
Online Access:https://doi.org/10.1186/s13073-021-00852-8

Internet

https://doi.org/10.1186/s13073-021-00852-8

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