The aftermath of COVID-19 pandemic on the diagnosis of TB at a tertiary care hospital in India
Background: The recent COVID-19 pandemic became a looming catastrophe over global public health and severely disrupted essential healthcare services like tuberculosis (TB). This study estimated the impact of the COVID-19 in the diagnosis of TB, a microbiology laboratory-based overview. Method: This...
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doaj-00d0039220b4495b94949e29b19ef5f32021-07-31T04:38:12ZengElsevierJournal of Infection and Public Health1876-03412021-08-0114810951098The aftermath of COVID-19 pandemic on the diagnosis of TB at a tertiary care hospital in IndiaDruti Hazra0Kiran Chawla1Vishnu P. Shenoy2Akhilesh K. Pandey3Nayana S4Department of Microbiology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka 576104, IndiaDepartment of Microbiology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka 576104, India; Corresponding authors.Department of Microbiology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka 576104, India; Corresponding authors.Department of Community Medicine, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka 576104, IndiaDepartment of Microbiology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka 576104, IndiaBackground: The recent COVID-19 pandemic became a looming catastrophe over global public health and severely disrupted essential healthcare services like tuberculosis (TB). This study estimated the impact of the COVID-19 in the diagnosis of TB, a microbiology laboratory-based overview. Method: This ambispective observational study was conducted at the Department of Microbiology in a tertiary care hospital in South Karnataka from January 2019 to December 2020. A standardized data collection sheet was prepared to collect the month-wise total number of suspected TB and confirmed TB samples. Data were analyzed using EZR 3.4.3 (R, open-source). Categorical variables were expressed in frequency and percentage. The Chi-square test was performed to test the difference in proportions and p < 0.05 indicated statistical significance. Results: In this study, a significant drop was observed in suspected TB specimens in 2020 compared to 2019, i.e. 54.8% for microscopy, along with 34.2% and 49.7% for Xpert MTB/RIF and MGIT culture respectively. Also, a sharp decline in confirmed TB samples was noted in 2020 with 49%, 43.8%, and 59.7% reduction with microscopy, Xpert MTB/RIF, and MGIT culture respectively, compared to 2019. Another major finding from this study reveals the PTB: EPTB proportion changed from 2.7:1 in 2019 to 2.1:1 in 2020, divulging an overall increase in EPTB sample proportion in 2020 (p = 0.0385). Conclusion: The COVID-19 pandemic adversely impacted the TB diagnostic services, resulting in a significant reduction of active TB case detection. It highlights an urgent need to revise the strategies to control and eliminate TB in this hour of the pandemic crisis.http://www.sciencedirect.com/science/article/pii/S187603412100188XCOVID-19TB diagnosticsEnd TBImpactPulmonary tuberculosisExtra-pulmonary tuberculosis |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Druti Hazra Kiran Chawla Vishnu P. Shenoy Akhilesh K. Pandey Nayana S |
spellingShingle |
Druti Hazra Kiran Chawla Vishnu P. Shenoy Akhilesh K. Pandey Nayana S The aftermath of COVID-19 pandemic on the diagnosis of TB at a tertiary care hospital in India Journal of Infection and Public Health COVID-19 TB diagnostics End TB Impact Pulmonary tuberculosis Extra-pulmonary tuberculosis |
author_facet |
Druti Hazra Kiran Chawla Vishnu P. Shenoy Akhilesh K. Pandey Nayana S |
author_sort |
Druti Hazra |
title |
The aftermath of COVID-19 pandemic on the diagnosis of TB at a tertiary care hospital in India |
title_short |
The aftermath of COVID-19 pandemic on the diagnosis of TB at a tertiary care hospital in India |
title_full |
The aftermath of COVID-19 pandemic on the diagnosis of TB at a tertiary care hospital in India |
title_fullStr |
The aftermath of COVID-19 pandemic on the diagnosis of TB at a tertiary care hospital in India |
title_full_unstemmed |
The aftermath of COVID-19 pandemic on the diagnosis of TB at a tertiary care hospital in India |
title_sort |
aftermath of covid-19 pandemic on the diagnosis of tb at a tertiary care hospital in india |
publisher |
Elsevier |
series |
Journal of Infection and Public Health |
issn |
1876-0341 |
publishDate |
2021-08-01 |
description |
Background: The recent COVID-19 pandemic became a looming catastrophe over global public health and severely disrupted essential healthcare services like tuberculosis (TB). This study estimated the impact of the COVID-19 in the diagnosis of TB, a microbiology laboratory-based overview. Method: This ambispective observational study was conducted at the Department of Microbiology in a tertiary care hospital in South Karnataka from January 2019 to December 2020. A standardized data collection sheet was prepared to collect the month-wise total number of suspected TB and confirmed TB samples. Data were analyzed using EZR 3.4.3 (R, open-source). Categorical variables were expressed in frequency and percentage. The Chi-square test was performed to test the difference in proportions and p < 0.05 indicated statistical significance. Results: In this study, a significant drop was observed in suspected TB specimens in 2020 compared to 2019, i.e. 54.8% for microscopy, along with 34.2% and 49.7% for Xpert MTB/RIF and MGIT culture respectively. Also, a sharp decline in confirmed TB samples was noted in 2020 with 49%, 43.8%, and 59.7% reduction with microscopy, Xpert MTB/RIF, and MGIT culture respectively, compared to 2019. Another major finding from this study reveals the PTB: EPTB proportion changed from 2.7:1 in 2019 to 2.1:1 in 2020, divulging an overall increase in EPTB sample proportion in 2020 (p = 0.0385). Conclusion: The COVID-19 pandemic adversely impacted the TB diagnostic services, resulting in a significant reduction of active TB case detection. It highlights an urgent need to revise the strategies to control and eliminate TB in this hour of the pandemic crisis. |
topic |
COVID-19 TB diagnostics End TB Impact Pulmonary tuberculosis Extra-pulmonary tuberculosis |
url |
http://www.sciencedirect.com/science/article/pii/S187603412100188X |
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