Inhibition of mesothelin as a novel strategy for targeting cancer cells.

Mesothelin, a differentiation antigen present in a series of malignancies such as mesothelioma, ovarian, lung and pancreatic cancer, has been studied as a marker for diagnosis and a target for immunotherapy. We, however, were interested in evaluating the effects of direct targeting of Mesothelin on...

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Bibliographic Details
Main Authors: Kun Wang, Vidya Bodempudi, Zhengian Liu, Emma Borrego-Diaz, Farnaz Yamoutpoor, Anna Meyer, Richard A Woo, Weihong Pan, Arkadiusz Z Dudek, Mojtaba S Olyaee, Tuba Esfandyari, Faris Farassati
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3317639?pdf=render