Interaction of Noradrenergic Pharmacological Manipulation and Subthalamic Stimulation on Movement Initiation Control in Parkinson's Disease

Interaction of Noradrenergic Pharmacological Manipulation and Subthalamic Stimulation on Movement Initiation Control in Parkinson's Disease

Background: Slowness in movement initiation (akinesia) is a cardinal feature of Parkinson's disease (PD), which is still poorly understood. Notably, akinesia is restored by subthalamic nucleus deep brain stimulation (STN-DBS) but not fully reversed by current dopaminergic treatments. It was rec...

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Bibliographic Details
Main Authors: Marion Albares, Stéphane Thobois, Emilie Favre, Emmanuel Broussolle, Gustavo Polo, Philippe Domenech, Philippe Boulinguez, Bénédicte Ballanger
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Brain Stimulation
Subjects:
Noradrenaline
STN-DBS
Akinesia
Reaction time
Executive control
Online Access:http://www.sciencedirect.com/science/article/pii/S1935861X14003106

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http://www.sciencedirect.com/science/article/pii/S1935861X14003106

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