Activation of Necroptosis in Multiple Sclerosis

Activation of Necroptosis in Multiple Sclerosis

Multiple sclerosis (MS), a common neurodegenerative disease of the CNS, is characterized by the loss of oligodendrocytes and demyelination. Tumor necrosis factor α (TNF-α), a proinflammatory cytokine implicated in MS, can activate necroptosis, a necrotic cell death pathway regulated by RIPK1 and RIP...

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Bibliographic Details
Main Authors: Dimitry Ofengeim, Yasushi Ito, Ayaz Najafov, Yaoyang Zhang, Bing Shan, Judy Park DeWitt, Juanying Ye, Xumin Zhang, Ansi Chang, Helin Vakifahmetoglu-Norberg, Jiefei Geng, Benedicte Py, Wen Zhou, Palak Amin, Jonilson Berlink Lima, Chunting Qi, Qiang Yu, Bruce Trapp, Junying Yuan
Format: Article
Language:English
Published: Elsevier 2015-03-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715002090

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http://www.sciencedirect.com/science/article/pii/S2211124715002090

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