Design, Synthesis and Applications of Hyaluronic Acid-Paclitaxel Bioconjugatesâ€

Paclitaxel (1a), a well known antitumor agent adopted mainly for the treatmentof breast and ovarian cancer, suffers from significant disadvantages such as low solubility,certain toxicity and specific drug-resistance of some tumor cells. To overcome theseproblems extensive research has been carried o...

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Bibliographic Details
Main Authors: Rinaldo Marini Bettolo, Luisa Maria Migneco, Angela La Bella, Francesca Leonelli
Format: Article
Language:English
Published: MDPI AG 2008-02-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/13/2/360/