Antiviral activity of mitoxantrone dihydrochloride against human herpes simplex virus mediated by suppression of the viral immediate early genes

Abstract Background HSV-1 is a common pathogen that infects 50–90% of the human population worldwide. HSV-1 causes numerous infection-related diseases, some of which are severely life-threatening. There are antiviral medications with activity against HSV-1. However, with the emergence of drug-resist...

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Bibliographic Details
Main Authors: Qiang Huang, Jue Hou, Peng Yang, Jun Yan, Xiaoliang Yu, Ying Zhuo, Sudan He, Feng Xu
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Microbiology
Subjects:
Online Access:https://doi.org/10.1186/s12866-019-1639-8