The burden of diabetes and hyperglycemia in Brazil: a global burden of disease study 2017
Abstract Background The Global Burden of Diseases (GBD) 2017 database permits an up-to-date evaluation of the frequency and burden of diabetes at the state level in Brazil and by type of diabetes. The objective of this report is to describe, using these updated GBD data, the current and projected fu...
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doaj-021f893f47424330ba15ea334b375a6c2020-11-25T03:16:20ZengBMCPopulation Health Metrics1478-79542020-09-0118S111110.1186/s12963-020-00209-0The burden of diabetes and hyperglycemia in Brazil: a global burden of disease study 2017Bruce Bartholow Duncan0Ewerton Cousin1Mohsen Naghavi2Ashkan Afshin3Elisabeth Barboza França4Valéria Maria de Azeredo Passos5Deborah Malta6Bruno R. Nascimento7Maria Inês Schmidt8Programa de Pós-graduação em Epidemiologia e Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do SulPrograma de Pós-graduação em Epidemiologia e Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do SulInstitute for Health Metrics and Evaluation, University of WashingtonInstitute for Health Metrics and Evaluation, University of WashingtonPrograma de Pós-graduação em Saúde Pública, Universidade Federal de Minas GeraisFaculdade Ciências Médicas de Minas GeraisDepartamento de Enfermagem Materno-Infantil e Saúde Pública, Escola de Enfermagem, Universidade Federal de Minas GeraisHospital das Clínicas da Universidade Federal de Minas GeraisPrograma de Pós-graduação em Epidemiologia e Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do SulAbstract Background The Global Burden of Diseases (GBD) 2017 database permits an up-to-date evaluation of the frequency and burden of diabetes at the state level in Brazil and by type of diabetes. The objective of this report is to describe, using these updated GBD data, the current and projected future burden of diabetes and hyperglycemia in Brazil, as well as its variation over time and space. Methods We derived all estimates using the GBD 2016 and 2017 databases to characterize disease burden related to diabetes and hyperglycemia in Brazil, from 1990 to 2040, using standard GBD methodologies. Results The overall estimated prevalence of diabetes in Brazil in 2017 was 4.4% (95%UI 4.0–4.9%), with 4.0% of those with diabetes being identified as having type 1 disease. While the crude prevalence of type 1 disease has remained relatively stable from 1990, type 2 prevalence has increased 30% for males and 26% for females. In 2017, approximately 3.3% of all disability-adjusted life years lost were due to diabetes and 5.9% to hyperglycemia. Diabetes prevalence and mortality were highest in the Northeast region and growing fastest in the North, Northeast, and Center-West regions. Over this period, despite a slight decrease in age-standardized incidence of type 2 diabetes, crude overall burden due to hyperglycemia has increased 19%, with population aging being a main cause for this rise. Cardiovascular diseases, responsible for 38.3% of this burden in 1990, caused only 25.9% of it in 2017, with premature mortality attributed directly to diabetes causing 31.6% of the 2017 burden. Future projections suggest that the diabetes mortality burden will increase 144% by 2040, more than twice the expected increase in crude disease burden overall (54%). By 2040, diabetes is projected to be Brazil’s third leading cause of death and hyperglycemia its third leading risk factor, in terms of deaths. Conclusions The disease burden in Brazil attributable to diabetes and hyperglycemia, already large, is predicted by GBD estimates to more than double to 2040. Strong actions by the Ministry of Health are necessary to counterbalance the major deleterious effects of population aging.http://link.springer.com/article/10.1186/s12963-020-00209-0Diabetes mellitushyperglycemiaepidemiologyGlobal Burden of DiseaseBrazil |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Bruce Bartholow Duncan Ewerton Cousin Mohsen Naghavi Ashkan Afshin Elisabeth Barboza França Valéria Maria de Azeredo Passos Deborah Malta Bruno R. Nascimento Maria Inês Schmidt |
spellingShingle |
Bruce Bartholow Duncan Ewerton Cousin Mohsen Naghavi Ashkan Afshin Elisabeth Barboza França Valéria Maria de Azeredo Passos Deborah Malta Bruno R. Nascimento Maria Inês Schmidt The burden of diabetes and hyperglycemia in Brazil: a global burden of disease study 2017 Population Health Metrics Diabetes mellitus hyperglycemia epidemiology Global Burden of Disease Brazil |
author_facet |
Bruce Bartholow Duncan Ewerton Cousin Mohsen Naghavi Ashkan Afshin Elisabeth Barboza França Valéria Maria de Azeredo Passos Deborah Malta Bruno R. Nascimento Maria Inês Schmidt |
author_sort |
Bruce Bartholow Duncan |
title |
The burden of diabetes and hyperglycemia in Brazil: a global burden of disease study 2017 |
title_short |
The burden of diabetes and hyperglycemia in Brazil: a global burden of disease study 2017 |
title_full |
The burden of diabetes and hyperglycemia in Brazil: a global burden of disease study 2017 |
title_fullStr |
The burden of diabetes and hyperglycemia in Brazil: a global burden of disease study 2017 |
title_full_unstemmed |
The burden of diabetes and hyperglycemia in Brazil: a global burden of disease study 2017 |
title_sort |
burden of diabetes and hyperglycemia in brazil: a global burden of disease study 2017 |
publisher |
BMC |
series |
Population Health Metrics |
issn |
1478-7954 |
publishDate |
2020-09-01 |
description |
Abstract Background The Global Burden of Diseases (GBD) 2017 database permits an up-to-date evaluation of the frequency and burden of diabetes at the state level in Brazil and by type of diabetes. The objective of this report is to describe, using these updated GBD data, the current and projected future burden of diabetes and hyperglycemia in Brazil, as well as its variation over time and space. Methods We derived all estimates using the GBD 2016 and 2017 databases to characterize disease burden related to diabetes and hyperglycemia in Brazil, from 1990 to 2040, using standard GBD methodologies. Results The overall estimated prevalence of diabetes in Brazil in 2017 was 4.4% (95%UI 4.0–4.9%), with 4.0% of those with diabetes being identified as having type 1 disease. While the crude prevalence of type 1 disease has remained relatively stable from 1990, type 2 prevalence has increased 30% for males and 26% for females. In 2017, approximately 3.3% of all disability-adjusted life years lost were due to diabetes and 5.9% to hyperglycemia. Diabetes prevalence and mortality were highest in the Northeast region and growing fastest in the North, Northeast, and Center-West regions. Over this period, despite a slight decrease in age-standardized incidence of type 2 diabetes, crude overall burden due to hyperglycemia has increased 19%, with population aging being a main cause for this rise. Cardiovascular diseases, responsible for 38.3% of this burden in 1990, caused only 25.9% of it in 2017, with premature mortality attributed directly to diabetes causing 31.6% of the 2017 burden. Future projections suggest that the diabetes mortality burden will increase 144% by 2040, more than twice the expected increase in crude disease burden overall (54%). By 2040, diabetes is projected to be Brazil’s third leading cause of death and hyperglycemia its third leading risk factor, in terms of deaths. Conclusions The disease burden in Brazil attributable to diabetes and hyperglycemia, already large, is predicted by GBD estimates to more than double to 2040. Strong actions by the Ministry of Health are necessary to counterbalance the major deleterious effects of population aging. |
topic |
Diabetes mellitus hyperglycemia epidemiology Global Burden of Disease Brazil |
url |
http://link.springer.com/article/10.1186/s12963-020-00209-0 |
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