18F-FDG-PET Detects Drastic Changes in Brain Metabolism in the Tg4–42 Model of Alzheimer’s Disease

18F-FDG-PET Detects Drastic Changes in Brain Metabolism in the Tg4–42 Model of Alzheimer’s Disease

The evaluation of new therapeutic strategies in Alzheimer’s disease (AD) relies heavily on in vivo imaging and suitable animal models that mimic the pathological changes seen in patients. 18F-Fluorodeoxyglucose (18F-FDG)-positron-emission tomography (PET) is a well-established non-invasive imaging t...

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Bibliographic Details
Main Authors: Caroline Bouter, Philipp Henniges, Timon N. Franke, Caroline Irwin, Carsten Oliver Sahlmann, Marius E. Sichler, Nicola Beindorff, Thomas A. Bayer, Yvonne Bouter
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Aging Neuroscience
Subjects:
positron-emission tomography
18F-Fluorodeoxyglucose
brain metabolism
Alzheimer’s disease
N-truncated Aβ
neuron loss
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2018.00425/full

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https://www.frontiersin.org/article/10.3389/fnagi.2018.00425/full

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