The Association of Physical Function Measures With Frailty, Falls History, and Metabolic Syndrome in a Population With Complex Obesity

Background: Frailty, falls and metabolic syndrome are known to be associated with poorer physical function. This study builds on available research by further investigating the relationship between physical function measures, including those comprising frailty, with metabolic syndrome (MetS) and fal...

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Main Authors: Amanda Rhynehart, Colin Dunlevy, Katie Hayes, Jean O'Connell, Donal O'Shea, Emer O'Malley
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Rehabilitation Sciences
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fresc.2021.716392/full
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spelling doaj-029045d6f7834f629d501cb5b3fcecc82021-09-16T04:40:06ZengFrontiers Media S.A.Frontiers in Rehabilitation Sciences2673-68612021-09-01210.3389/fresc.2021.716392716392The Association of Physical Function Measures With Frailty, Falls History, and Metabolic Syndrome in a Population With Complex ObesityAmanda Rhynehart0Colin Dunlevy1Katie Hayes2Jean O'Connell3Jean O'Connell4Donal O'Shea5Donal O'Shea6Emer O'Malley7Weight Management Service, St Columcille's Hospital, Dublin, IrelandWeight Management Service, St Columcille's Hospital, Dublin, IrelandWeight Management Service, St Columcille's Hospital, Dublin, IrelandWeight Management Service, St Columcille's Hospital, Dublin, IrelandObesity Research Group, St Vincent's University Hospital, Dublin, IrelandWeight Management Service, St Columcille's Hospital, Dublin, IrelandObesity Research Group, St Vincent's University Hospital, Dublin, IrelandWeight Management Service, St Columcille's Hospital, Dublin, IrelandBackground: Frailty, falls and metabolic syndrome are known to be associated with poorer physical function. This study builds on available research by further investigating the relationship between physical function measures, including those comprising frailty, with metabolic syndrome (MetS) and falls, in the context of complex obesity.Methods: Participants were recruited from the national Level 3 weight management service in Ireland. A retrospective audit of data gathered at initial assessment was performed. Data included past medical history, blood tests, blood pressure measurement, anthropometrics, falls history, self-reported physical activity levels (PALs) and physical function measures, including hand grip strength (HGS), “timed up and go” (TUG), functional reach (FR), sit to stand (STS) and gait speed. A modified version of the Fried Frailty Index was employed.Results: Of the 713 participants, 65.1% (n = 464) were female and 34.9% (n = 249) were male with a mean age of 44.2 (±11.7) years and body mass index (BMI) of 50.6 kg/m2 (±8.2). Frailty was identified in 3.4% (n = 24), falls in 28.8% (n = 205) and MetS in 55.1% (n = 393). Frailty was associated with older age (53.8 ± 14.3 vs. 43.9 ± 11.5 years), poorer PALs (27.29 ± 46.3 vs. 101.1 ± 147.4 min/wk), reduced grip strength (17.7 ± 4.6 vs. 34.2 ± 11.0 Kg) longer STS (21.7 ± 6.6 vs. 13.7 ± 5.7 s), shorter functional reach (29.7 ± 7.9 vs. 37.9 ± 8.2 cm) and slower gait speed (0.6 ± 0.2 vs. 1.1 ± 0.5 m/s). Those reporting a falls history had a reduced FR (35.8 ± 8.9 vs. 38.3 ± 7.8 cm) and slower STS (15.4 ± 8.0 vs. 13.3 ± 4.7 s). Participants with MetS had lower PALs (83.2 ± 128.2 vs. 119.2 ± 157.6) and gait speed (1.1 ± 0.3 vs. 1.2 ± 0.7 m/s). There was no difference in BMI between fallers and non-fallers (51.34 ± 8.44 vs. 50.33 ± 8.13 Kg/m2, p = 0.138), nor between those with or without MetS. Significant associations were found between BMI and all physical function measures except the TUAG.Conclusion: The associations between frailty, falls and MetS and their combined impact on physical function in people living with obesity demonstrates the need for appropriate screening. Utilising grip strength and gait speed to identify frailty in those with obesity and metabolic syndrome could help target therapies aimed at improving strength, physical function and ultimately quality of life.https://www.frontiersin.org/articles/10.3389/fresc.2021.716392/fullphysical functionfrailtyfallsfalls historymetabolic syndromeobesity
collection DOAJ
language English
format Article
sources DOAJ
author Amanda Rhynehart
Colin Dunlevy
Katie Hayes
Jean O'Connell
Jean O'Connell
Donal O'Shea
Donal O'Shea
Emer O'Malley
spellingShingle Amanda Rhynehart
Colin Dunlevy
Katie Hayes
Jean O'Connell
Jean O'Connell
Donal O'Shea
Donal O'Shea
Emer O'Malley
The Association of Physical Function Measures With Frailty, Falls History, and Metabolic Syndrome in a Population With Complex Obesity
Frontiers in Rehabilitation Sciences
physical function
frailty
falls
falls history
metabolic syndrome
obesity
author_facet Amanda Rhynehart
Colin Dunlevy
Katie Hayes
Jean O'Connell
Jean O'Connell
Donal O'Shea
Donal O'Shea
Emer O'Malley
author_sort Amanda Rhynehart
title The Association of Physical Function Measures With Frailty, Falls History, and Metabolic Syndrome in a Population With Complex Obesity
title_short The Association of Physical Function Measures With Frailty, Falls History, and Metabolic Syndrome in a Population With Complex Obesity
title_full The Association of Physical Function Measures With Frailty, Falls History, and Metabolic Syndrome in a Population With Complex Obesity
title_fullStr The Association of Physical Function Measures With Frailty, Falls History, and Metabolic Syndrome in a Population With Complex Obesity
title_full_unstemmed The Association of Physical Function Measures With Frailty, Falls History, and Metabolic Syndrome in a Population With Complex Obesity
title_sort association of physical function measures with frailty, falls history, and metabolic syndrome in a population with complex obesity
publisher Frontiers Media S.A.
series Frontiers in Rehabilitation Sciences
issn 2673-6861
publishDate 2021-09-01
description Background: Frailty, falls and metabolic syndrome are known to be associated with poorer physical function. This study builds on available research by further investigating the relationship between physical function measures, including those comprising frailty, with metabolic syndrome (MetS) and falls, in the context of complex obesity.Methods: Participants were recruited from the national Level 3 weight management service in Ireland. A retrospective audit of data gathered at initial assessment was performed. Data included past medical history, blood tests, blood pressure measurement, anthropometrics, falls history, self-reported physical activity levels (PALs) and physical function measures, including hand grip strength (HGS), “timed up and go” (TUG), functional reach (FR), sit to stand (STS) and gait speed. A modified version of the Fried Frailty Index was employed.Results: Of the 713 participants, 65.1% (n = 464) were female and 34.9% (n = 249) were male with a mean age of 44.2 (±11.7) years and body mass index (BMI) of 50.6 kg/m2 (±8.2). Frailty was identified in 3.4% (n = 24), falls in 28.8% (n = 205) and MetS in 55.1% (n = 393). Frailty was associated with older age (53.8 ± 14.3 vs. 43.9 ± 11.5 years), poorer PALs (27.29 ± 46.3 vs. 101.1 ± 147.4 min/wk), reduced grip strength (17.7 ± 4.6 vs. 34.2 ± 11.0 Kg) longer STS (21.7 ± 6.6 vs. 13.7 ± 5.7 s), shorter functional reach (29.7 ± 7.9 vs. 37.9 ± 8.2 cm) and slower gait speed (0.6 ± 0.2 vs. 1.1 ± 0.5 m/s). Those reporting a falls history had a reduced FR (35.8 ± 8.9 vs. 38.3 ± 7.8 cm) and slower STS (15.4 ± 8.0 vs. 13.3 ± 4.7 s). Participants with MetS had lower PALs (83.2 ± 128.2 vs. 119.2 ± 157.6) and gait speed (1.1 ± 0.3 vs. 1.2 ± 0.7 m/s). There was no difference in BMI between fallers and non-fallers (51.34 ± 8.44 vs. 50.33 ± 8.13 Kg/m2, p = 0.138), nor between those with or without MetS. Significant associations were found between BMI and all physical function measures except the TUAG.Conclusion: The associations between frailty, falls and MetS and their combined impact on physical function in people living with obesity demonstrates the need for appropriate screening. Utilising grip strength and gait speed to identify frailty in those with obesity and metabolic syndrome could help target therapies aimed at improving strength, physical function and ultimately quality of life.
topic physical function
frailty
falls
falls history
metabolic syndrome
obesity
url https://www.frontiersin.org/articles/10.3389/fresc.2021.716392/full
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