Human Neutrophils Produce Antifungal Extracellular Vesicles against Aspergillus fumigatus

Human Neutrophils Produce Antifungal Extracellular Vesicles against Aspergillus fumigatus

Invasive fungal infections caused by the mold Aspergillus fumigatus are a growing concern in the clinic due to the increasing use of immunosuppressive therapies and increasing antifungal drug resistance. These infections result in high rates of mortality, as treatment and diagnostic options remain l...

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Bibliographic Details
Main Authors: Iordana A. Shopova, Ivan Belyaev, Prasad Dasari, Susanne Jahreis, Maria C. Stroe, Zoltán Cseresnyés, Ann-Kathrin Zimmermann, Anna Medyukhina, Carl-Magnus Svensson, Thomas Krüger, Viktòria Szeifert, Sandor Nietzsche, Theresia Conrad, Matthew G. Blango, Olaf Kniemeyer, Marie von Lilienfeld-Toal, Peter F. Zipfel, Erzsébet Ligeti, Marc Thilo Figge, Axel A. Brakhage
Format: Article
Language:English
Published: American Society for Microbiology 2020-04-01
Series:mBio
Subjects:
aspergillus fumigatus
azurocidin
cathepsin g
extracellular vesicle
fluorescent image analysis
fungi
microvesicle
neutrophils
polymorphonuclear leukocytes
Online Access:https://doi.org/10.1128/mBio.00596-20

Internet

https://doi.org/10.1128/mBio.00596-20

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