Formulation development and optimization of Lamivudine 300 mg and Tenofovir Disoproxil Fumarate (TDF) 300 mg FDC tablets by D-optimal mixture design

The usage of fixed dose combination (FDC) tablets of Lamivudine and Tenofovir Disoproxil Fumarate (TDF) is increasing due to increased incidences of HIV/Hepatitis B and HIV/TB co-infections. This is likely to increase the financial crisis due to limited resources for funding procurement of ready-mad...

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Bibliographic Details
Main Authors: Prosper Tibalinda, Joseph Sempombe, Raphael Shedafa, Nelson Masota, Dickson Pius, Mary Temu, Eliangiringa Kaale
Format: Article
Language:English
Published: Elsevier 2016-12-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S240584401631249X