Improving Multi-Epitope Long Peptide Vaccine Potency by Using a Strategy that Enhances CD4+ T Help in BALB/c Mice.

Peptide-based vaccines are attractive approaches for cancer immunotherapy; but the success of these vaccines in clinical trials have been limited. Our goal is to improve immune responses and anti-tumor effects against a synthetic, multi-epitope, long peptide from rat Her2/neu (rHer2/neu) using the h...

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Bibliographic Details
Main Authors: Haniyeh Ghaffari-Nazari, Jalil Tavakkol-Afshari, Mahmoud Reza Jaafari, Sahar Tahaghoghi-Hajghorbani, Elham Masoumi, Seyed Amir Jalali
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4640540?pdf=render