Protein tyrosine phosphatase PTPN1 modulates cell growth and associates with poor outcome in human neuroblastoma

Protein tyrosine phosphatase PTPN1 modulates cell growth and associates with poor outcome in human neuroblastoma

Abstract Background Protein tyrosine phosphatases (PTPs) regulate neuronal differentiation and survival, but their expression patterns and functions in human neuroblastoma (NB) are scarcely known. Here, we have investigated the function and expression of the non-receptor PTPN1 on human NB cell lines...

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Bibliographic Details
Main Authors: Caroline E. Nunes-Xavier, Olaia Aurtenetxe, Laura Zaldumbide, Ricardo López-Almaraz, Asier Erramuzpe, Jesús M. Cortés, José I. López, Rafael Pulido
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Diagnostic Pathology
Subjects:
Neuroblastoma
Neuroblastoma differentiation
Metastatic neuroblastoma
Protein tyrosine phosphatases
PTPN1
Online Access:https://doi.org/10.1186/s13000-019-0919-9

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