The different roles of glucocorticoids in the hippocampus and hypothalamus in chronic stress-induced HPA axis hyperactivity.

The different roles of glucocorticoids in the hippocampus and hypothalamus in chronic stress-induced HPA axis hyperactivity.

Hypothalamus-pituitary-adrenal (HPA) hyperactivity is observed in many patients suffering from depression and the mechanism underling the dysfunction of HPA axis is not well understood. Chronic stress has a causal relationship with the hyperactivity of HPA axis. Stress induces the over-synthesis of...

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Bibliographic Details
Main Authors: Li-Juan Zhu, Meng-Ying Liu, Huan Li, Xiao Liu, Chen Chen, Zhou Han, Hai-Yin Wu, Xing Jing, Hai-Hui Zhou, Hoonkyo Suh, Dong-Ya Zhu, Qi-Gang Zhou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4022669?pdf=render

Internet

http://europepmc.org/articles/PMC4022669?pdf=render

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