An effective protocol for pharmacological defatting of primary human hepatocytes which is non-toxic to cholangiocytes or intrahepatic endothelial cells.

INTRODUCTION:Pharmacological defatting of rat hepatocytes and hepatoma cell lines suggests that the same method could be used to ameliorate macrovesicular steatosis in moderate to severely fatty livers. However there is no data assessing the effects of those drugs on primary human liver cells. We ai...

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Bibliographic Details
Main Authors: Yuri L Boteon, Lorraine Wallace, Amanda P C S Boteon, Darius F Mirza, Hynek Mergental, Ricky H Bhogal, Simon Afford
Format: Article
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
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