Stents Eluting 6-Mercaptopurine Reduce Neointima Formation and Inflammation while Enhancing Strut Coverage in Rabbits.

Stents Eluting 6-Mercaptopurine Reduce Neointima Formation and Inflammation while Enhancing Strut Coverage in Rabbits.

The introduction of drug-eluting stents (DES) has dramatically reduced restenosis rates compared with bare metal stents, but in-stent thrombosis remains a safety concern, necessitating prolonged dual anti-platelet therapy. The drug 6-Mercaptopurine (6-MP) has been shown to have beneficial effects in...

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Bibliographic Details
Main Authors: Matthijs S Ruiter, Claudia M van Tiel, Albert Doornbos, Goran Marinković, Aart C Strang, Nico J M Attevelt, Vivian de Waard, Robbert J de Winter, Rob Steendam, Carlie J M de Vries
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4577071?pdf=render

Internet

http://europepmc.org/articles/PMC4577071?pdf=render

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