FOXA1 Gene Expression for Defining Molecular Subtypes of Muscle-Invasive Bladder Cancer after Radical Cystectomy

FOXA1 Gene Expression for Defining Molecular Subtypes of Muscle-Invasive Bladder Cancer after Radical Cystectomy

It remains unclear how to implement the recently revealed basal and luminal subtypes of muscle-invasive bladder cancer (MIBC) into daily clinical routine and whether molecular marker panels can be reduced. The mRNA expression of basal (KRT5) and luminal (FOXA1, GATA3, KRT20) markers was measured by...

Full description

Bibliographic Details
Main Authors: Danijel Sikic, Markus Eckstein, Ralph M. Wirtz, Jonas Jarczyk, Thomas S. Worst, Stefan Porubsky, Bastian Keck, Frank Kunath, Veronika Weyerer, Johannes Breyer, Wolfgang Otto, Sebastien Rinaldetti, Christian Bolenz, Arndt Hartmann, Bernd Wullich, Philipp Erben
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Journal of Clinical Medicine
Subjects:
FOXA1
GATA3
KRT20
molecular markers
mRNA
muscle-invasive bladder cancer
Online Access:https://www.mdpi.com/2077-0383/9/4/994

Internet

https://www.mdpi.com/2077-0383/9/4/994

Similar Items