AIF-1 gene does not confer susceptibility to Behçet's disease: Analysis of extended haplotypes in Sardinian population.

BACKGROUND:Behçet's disease (BD) is a polygenic immune-mediated disorder characterized by a close association with the HLA-B*51 allele. The HLA region has a strong linkage disequilibrium (LD) and carries several genetic variants (e.g. MIC-A, TNF-α genes) identified as associated to BD because o...

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Main Authors: Maria Maddalena Angioni, Matteo Piga, Fabiana Paladini, Sara Lai, Gian Luca Erre, Alberto Floris, Alberto Cauli, Maria Teresa Fiorillo, Giuseppe Passiu, Carlo Carcassi, Rosa Sorrentino, Alessandro Mathieu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6155533?pdf=render