Modeling high-grade serous carcinoma: how converging insights into pathogenesis and genetics are driving better experimental platforms

Recent developments in the study of epithelial ovarian cancer have called into question the traditional views regarding the site of tumor initiation. Histopathologic studies and genomic analyses suggest that extra-ovarian sites, like the fallopian tube, may harbor the coveted cell of origin and cou...

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Bibliographic Details
Main Authors: Paul Michael Jones, Ronny eDrapkin
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-08-01
Series:Frontiers in Oncology
Subjects:
OSE
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00217/full