Quantification of plasma cell dynamics using mathematical modelling

Plasma cells (PCs) are the main antibody-producing cells in humans. They are long-lived so that specific antibodies against either pathogens or vaccines are produced for decades. PC longevity is attributed to specific areas within the bone marrow micro-environment, the so-called ‘niche’, providing t...

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Bibliographic Details
Main Authors: Marcel Mohr, Dirk Hose, Anja Seckinger, Anna Marciniak-Czochra
Format: Article
Language:English
Published: The Royal Society 2018-01-01
Series:Royal Society Open Science
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.170759