Combination of interleukin-10 gene promoter polymorphisms with HLA-DRB1*15 allele is associated with multiple sclerosis

Combination of interleukin-10 gene promoter polymorphisms with HLA-DRB1*15 allele is associated with multiple sclerosis

Background & objectives: Multiple sclerosis (MS) is common in some ethnic groups. Interleukin-10 (IL-10) is a potent anti-inflammatory and immunosuppressive cytokine that may be an important regulator in MS disease pathogenesis. IL-10 promoter includes several single nucleotide polymorphisms and...

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Bibliographic Details
Main Authors: Majid Shahbazi, Javad Sadeghi Allah Abadi, Danial Roshandel, Maryam Koochaki, Hosein Amiri, Rahim Kohansal, Seied Mohammad Baghbanian, Mahdi Zamani
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Indian Journal of Medical Research
Subjects:
Cytokine - HLA-DRB1*15 allele - interleukin-10 - multiple sclerosis - single nucleotide polymorphism
Online Access:http://www.ijmr.org.in/article.asp?issn=0971-5916;year=2017;volume=145;issue=6;spage=746;epage=752;aulast=Shahbazi

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http://www.ijmr.org.in/article.asp?issn=0971-5916;year=2017;volume=145;issue=6;spage=746;epage=752;aulast=Shahbazi

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