Tauroursodeoxycholic Acid Alleviates HO-Induced Oxidative Stress and Apoptosis via Suppressing Endoplasmic Reticulum Stress in Neonatal Rat Cardiomyocytes

Introduction: We aimed to test the mechanism of protective effects of tauroursodeoxycholic acid (TUDCA) on cardiovascular disease using cultured cardiomyocytes. Methods: Neonatal rat cardiomyocytes (NRCMs) were isolated and cultured and then the cells were divided into 4 groups based on the treatmen...

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Bibliographic Details
Main Authors: Lin Zhang, Yanmin Wang
Format: Article
Language:English
Published: SAGE Publishing 2018-07-01
Series:Dose-Response
Online Access:https://doi.org/10.1177/1559325818782631