ST3Gal IV Mediates the Growth and Proliferation of Cervical Cancer Cells In Vitro and In Vivo Via the Notch/p21/CDKs Pathway

ST3Gal IV Mediates the Growth and Proliferation of Cervical Cancer Cells In Vitro and In Vivo Via the Notch/p21/CDKs Pathway

ST3Gal IV is one of the principal sialyltransferases responsible for the biosynthesis of α2, 3-sialic acid to the termini N-glycans or O-glycans of glycoproteins and glycolipids. It has been reported that ST3Gal IV expression is associated with gastric carcinoma, pancreatic adenocarcinoma and breast...

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Bibliographic Details
Main Authors: Yinshuang Wu, Xixi Chen, Weijie Dong, Zhongyang Xu, Yuli Jian, Chunyan Xu, Lin Zhang, Anwen Wei, Xiao Yu, Shidan Wang, Yue Wang, Gang Liu, Xiaoxin Sun, Shujing Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Oncology
Subjects:
ST3Gal IV
cervical cancer
α2
3-sialylation
cell proliferation
Notch signaling pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.540332/full

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