Recurrent respiratory papillomatosis with lower airway involvement in a young woman

• Main Authors: Tatiana Mamaeva, Camilla Slot Mehlum, Jesper Rømhild Davidsen
• Format: Article
• Language: English
• Published: Taylor & Francis Group 2020-01-01
• Series: European Clinical Respiratory Journal
• Subjects: rrp; recurrent respiratory papillomatosis; papillomas; rare disease; hpv; hrct; treatment
• Online Access: http://dx.doi.org/10.1080/20018525.2020.1740567

Radiological presentation of bronchiectasis should prompt the respiratory physician to investigate various differential diagnosis leading to this condition. This case report describes a young non-smoking woman with HPV11 induced laryngeal Recurrent Respiratory Papillomatosis (RRP) since early childhood, who developed progressive exertional dyspnea. A thorough diagnostic process revealed HPV11 infection in the lung parenchyma consistent with RRP in the lower airways, an HPV infection that was most likely obtained from the patient´s mother during vaginal birth. This case report illustrates that also respiratory physicians should keep RRP in mind in persons with the radiological presentation of bronchiectasis previously diagnosed RRP in the upper airways.