"Seed-Milarity" confers to hsa-miR-210 and hsa-miR-147b similar functional activity.

"Seed-Milarity" confers to hsa-miR-210 and hsa-miR-147b similar functional activity.

Specificity of interaction between a microRNA (miRNA) and its targets crucially depends on the seed region located in its 5'-end. It is often implicitly considered that two miRNAs sharing the same biological activity should display similarity beyond the strict six nucleotide region that forms t...

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Bibliographic Details
Main Authors: Thomas Bertero, Sébastien Grosso, Karine Robbe-Sermesant, Kevin Lebrigand, Imene-Sarah Hénaoui, Marie-Pierre Puisségur, Sandra Fourre, Laure-Emmanuelle Zaragosi, Nathalie M Mazure, Gilles Ponzio, Bruno Cardinaud, Pascal Barbry, Roger Rezzonico, Bernard Mari
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3441733?pdf=render

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http://europepmc.org/articles/PMC3441733?pdf=render

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