Evolution and diversity of clonal bacteria: the paradigm of Mycobacterium tuberculosis.

BACKGROUND: Mycobacterium tuberculosis complex species display relatively static genomes and 99.9% nucleotide sequence identity. Studying the evolutionary history of such monomorphic bacteria is a difficult and challenging task. PRINCIPAL FINDINGS: We found that single-nucleotide polymorphism (SNP)...

Full description

Bibliographic Details
Main Authors: Tiago Dos Vultos, Olga Mestre, Jean Rauzier, Marcin Golec, Nalin Rastogi, Voahangy Rasolofo, Tone Tonjum, Christophe Sola, Ivan Matic, Brigitte Gicquel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2211405?pdf=render