Role of the NC-loop in catalytic activity and stability in lipase from Fervidobacterium changbaicum.

Flexible NC-loops between the catalytic domain and the cap domain of the α/β hydrolase fold enzymes show remarkable diversity in length, sequence, and configuration. Recent investigations have suggested that the NC-loop might be involved in catalysis and substrate recognition in many enzymes from th...

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Bibliographic Details
Main Authors: Binchun Li, Guangyu Yang, Lie Wu, Yan Feng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3466181?pdf=render