Aptamer Efficacies for In Vitro and In Vivo Modulation of αC-Conotoxin PrXA Pharmacology

Aptamer Efficacies for In Vitro and In Vivo Modulation of αC-Conotoxin PrXA Pharmacology

The medical staff is often powerless to treat patients affected by drug abuse or misuse and poisoning. In the case of envenomation, the treatment of choice remains horse sera administration that poses a wealth of other medical conditions and threats. Previously, we have demonstrated that DNA-based a...

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Bibliographic Details
Main Authors: Germain Sotoing Taiwe, Jérôme Montnach, Sébastien Nicolas, Stéphan De Waard, Emmanuelle Fiore, Eric Peyrin, Tarek Mohamed Abd El-Aziz, Muriel Amar, Jordi Molgó, Michel Ronjat, Denis Servent, Corinne Ravelet, Michel De Waard
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Molecules
Subjects:
αC-conotoxin PrXA
DNA aptamer
oligonucleotide
toxin neutralization
cone peptide
venom
Online Access:http://www.mdpi.com/1420-3049/24/2/229

Internet

http://www.mdpi.com/1420-3049/24/2/229

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