Variant G57E of mannose binding lectin associated with protection against tuberculosis caused by Mycobacterium africanum but not by M. tuberculosis.

Structural variants of the Mannose Binding Lectin (MBL) cause quantitative and qualitative functional deficiencies, which are associated with various patterns of susceptibility to infectious diseases and other disorders. We determined genetic MBL variants in 2010 Ghanaian patients with pulmonary tub...

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Bibliographic Details
Main Authors: Thorsten Thye, Stefan Niemann, Kerstin Walter, Susanne Homolka, Christopher D Intemann, Margaret Amanua Chinbuah, Anthony Enimil, John Gyapong, Ivy Osei, Ellis Owusu-Dabo, Sabine Rüsch-Gerdes, Rolf D Horstmann, Stefan Ehlers, Christian G Meyer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3112207?pdf=render