Application of the adverse outcome pathway (AOP) concept to structure the available in vivo and in vitro mechanistic data for allergic sensitization to food proteins

Application of the adverse outcome pathway (AOP) concept to structure the available in vivo and in vitro mechanistic data for allergic sensitization to food proteins

Abstract Background The introduction of whole new foods in a population may lead to sensitization and food allergy. This constitutes a potential public health problem and a challenge to risk assessors and managers as the existing understanding of the pathophysiological processes and the currently av...

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Main Authors: Jolanda H. M. van Bilsen, Edyta Sienkiewicz-Szłapka, Daniel Lozano-Ojalvo, Linette E. M. Willemsen, Celia M. Antunes, Elena Molina, Joost J. Smit, Barbara Wróblewska, Harry J. Wichers, Edward F. Knol, Gregory S. Ladics, Raymond H. H. Pieters, Sandra Denery-Papini, Yvonne M. Vissers, Simona L. Bavaro, Colette Larré, Kitty C. M. Verhoeckx, Erwin L. Roggen
Format: Article
Language:English
Published: Wiley 2017-05-01
Series:Clinical and Translational Allergy
Subjects:
Adverse outcome pathway
Key events
Key event relations
Food allergy
Sensitization
Mechanistic understanding
Online Access:http://link.springer.com/article/10.1186/s13601-017-0152-0

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http://link.springer.com/article/10.1186/s13601-017-0152-0

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