Phyllanthus amarus prevents LPS-mediated BV2 microglial activation via MyD88 and NF-κB signaling pathways

Phyllanthus amarus prevents LPS-mediated BV2 microglial activation via MyD88 and NF-κB signaling pathways

Abstract Background Phyllanthus amarus has been shown to attenuate lipopolysaccharide (LPS)-induced peripheral inflammation but similar studies in the central nervous system are scarce. The aim of the present study was to investigate the neuroprotective effects of 80% ethanol extract of P. amarus (E...

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Bibliographic Details
Main Authors: Elysha Nur Ismail, Ibrahim Jantan, Sharmili Vidyadaran, Jamia Azdina Jamal, Norazrina Azmi
Format: Article
Language:English
Published: BMC 2020-07-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Phyllanthus amarus
Neuroprotection
Microglial activation
Neuroinflammation
BV2 microglial cells
Online Access:http://link.springer.com/article/10.1186/s12906-020-02961-0

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http://link.springer.com/article/10.1186/s12906-020-02961-0

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