The Predictors of Obesity Hypoventilation Syndrome in Obstructive Sleep Apnea
Background: As obesity increases, the frequency of obstructive sleep apnea and obesity hypoventilation syndrome increases also. However, obesity hypoventilation syndrome frequency is not known, as capnography and arterial blood gas analysis are not routinely performed in sleep laboratories. Aims: T...
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doaj-0636b920a59f4382873145e0ace3b9fe2020-11-25T02:09:39ZengGalenos Publishing HouseBalkan Medical Journal2146-31232146-31312017-02-013414146 10.4274/balkanmedj.2015.1797The Predictors of Obesity Hypoventilation Syndrome in Obstructive Sleep ApneaAylin Pıhtılı0Züleyha Bingöl1Esen Kıyan2Department of Pulmonary Medicine, İstanbul Haydarpaşa Numune Training and Research Hospital, İstanbul, Turkeyİstanbul University School of Medicine, Department of Pulmonary Medicine, İstanbul, Turkeyİstanbul University School of Medicine, Department of Pulmonary Medicine, İstanbul, TurkeyBackground: As obesity increases, the frequency of obstructive sleep apnea and obesity hypoventilation syndrome increases also. However, obesity hypoventilation syndrome frequency is not known, as capnography and arterial blood gas analysis are not routinely performed in sleep laboratories. Aims: To investigate the frequency and predictors of obesity hypoventilation syndrome in obese subjects. Study Design: Retrospective clinical study Methods: Obese subjects who had arterial blood gas analysis admitted to the sleep laboratory and polysomnography were retrospectively analyzed. Subjects with restrictive (except obesity) and obstructive pulmonary pathologies were excluded. Demographics, Epworth-Sleepiness-Scale scores, polysomnographic data, arterial blood gas analysis, and spirometric measurements were recorded. Results: Of the 419 subjects, 45.1% had obesity hypoventilation syndrome. Apnea hypopnea index (p<0.001), oxygen desaturation index (p<0.001) and sleep time with SpO2<90% (p<0.001) were statistically higher in subjects with obesity hypoventilation syndrome compared to subjects with eucapnic obstructive sleep apnea. The nocturnal mean SpO2 (p<0.001) and lowest SpO2 (p<0.001) were also statistically lower in subjects with obesity hypoventilation syndrome. Logistic regression analysis showed that the lowest SpO2, oxygen desaturation index, apnea hypopnea index and sleep time with SpO2 <90% were related factors for obesity hypoventilation syndrome. Conclusion: Obesity hypoventilation syndrome should be considered when oxygen desaturation index, apnea hypopnea index and sleep time with SpO2 <90% are highhttp://balkanmedicaljournal.org/text.php?lang=en&id=1637Apnea hypopnea indexhypercapniaobesityobesity hypoventilation syndromeobstructive sleep apnea |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Aylin Pıhtılı Züleyha Bingöl Esen Kıyan |
spellingShingle |
Aylin Pıhtılı Züleyha Bingöl Esen Kıyan The Predictors of Obesity Hypoventilation Syndrome in Obstructive Sleep Apnea Balkan Medical Journal Apnea hypopnea index hypercapnia obesity obesity hypoventilation syndrome obstructive sleep apnea |
author_facet |
Aylin Pıhtılı Züleyha Bingöl Esen Kıyan |
author_sort |
Aylin Pıhtılı |
title |
The Predictors of Obesity Hypoventilation Syndrome in Obstructive Sleep Apnea |
title_short |
The Predictors of Obesity Hypoventilation Syndrome in Obstructive Sleep Apnea |
title_full |
The Predictors of Obesity Hypoventilation Syndrome in Obstructive Sleep Apnea |
title_fullStr |
The Predictors of Obesity Hypoventilation Syndrome in Obstructive Sleep Apnea |
title_full_unstemmed |
The Predictors of Obesity Hypoventilation Syndrome in Obstructive Sleep Apnea |
title_sort |
predictors of obesity hypoventilation syndrome in obstructive sleep apnea |
publisher |
Galenos Publishing House |
series |
Balkan Medical Journal |
issn |
2146-3123 2146-3131 |
publishDate |
2017-02-01 |
description |
Background: As obesity increases, the frequency of obstructive sleep apnea and obesity hypoventilation syndrome increases also. However, obesity hypoventilation syndrome frequency is not known, as capnography and arterial blood gas analysis are not routinely performed in sleep laboratories.
Aims: To investigate the frequency and predictors of obesity hypoventilation syndrome in obese subjects.
Study Design: Retrospective clinical study
Methods: Obese subjects who had arterial blood gas analysis admitted to the sleep laboratory and polysomnography were retrospectively analyzed. Subjects with restrictive (except obesity) and obstructive pulmonary pathologies were excluded. Demographics, Epworth-Sleepiness-Scale scores, polysomnographic data, arterial blood gas analysis, and spirometric measurements were recorded.
Results: Of the 419 subjects, 45.1% had obesity hypoventilation syndrome. Apnea hypopnea index (p<0.001), oxygen desaturation index (p<0.001) and sleep time with SpO2<90% (p<0.001) were statistically higher in subjects with obesity hypoventilation syndrome compared to subjects with eucapnic obstructive sleep apnea. The nocturnal mean SpO2 (p<0.001) and lowest SpO2 (p<0.001) were also statistically lower in subjects with obesity hypoventilation syndrome. Logistic regression analysis showed that the lowest SpO2, oxygen desaturation index, apnea hypopnea index and sleep time with SpO2 <90% were related factors for obesity hypoventilation syndrome.
Conclusion: Obesity hypoventilation syndrome should be considered when oxygen desaturation index, apnea hypopnea index and sleep time with SpO2 <90% are high |
topic |
Apnea hypopnea index hypercapnia obesity obesity hypoventilation syndrome obstructive sleep apnea |
url |
http://balkanmedicaljournal.org/text.php?lang=en&id=1637 |
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