Serine and proline-rich ligands enriched via phage-display technology show preferential binding to BCR/ABL expressing cells

Background and objectives: Despite the use of targeted therapy, chronic myelogenous leukemia (CML) currently remains incurable with drug therapy, with patients requiring life-long treatment. Developing either a vaccine to prevent the disease or another novel drug to specifically target and eradicate...

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Bibliographic Details
Main Authors: Karen Shires, Iva Shankland, Shaheen Mowla, Samuel Njikan, Jai Jaymacker, Nicolas Novitzky
Format: Article
Language:English
Published: Elsevier 2014-03-01
Series:Hematology/Oncology and Stem Cell Therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S1658387614000028