DeconPeaker, a Deconvolution Model to Identify Cell Types Based on Chromatin Accessibility in ATAC-Seq Data of Mixture Samples

DeconPeaker, a Deconvolution Model to Identify Cell Types Based on Chromatin Accessibility in ATAC-Seq Data of Mixture Samples

While our understanding of cellular and molecular processes has grown exponentially, issues related to the cell microenvironment and cellular heterogeneity have sparked a new debate concerning the cell identity. Cell composition (chromatin and nuclear architecture) poses a strong risk for dynamic ch...

Full description

Bibliographic Details
Main Authors: Huamei Li, Amit Sharma, Kun Luo, Zhaohui S. Qin, Xiao Sun, Hongde Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Genetics
Subjects:
chromatin accessibility
cell type
deconvolution
mixture samples
gene expression
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.00392/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2020.00392/full

Similar Items