Clinical characteristics and outcome of patients with neuroblastoma presenting genomic amplification of loci other than MYCN.

Clinical characteristics and outcome of patients with neuroblastoma presenting genomic amplification of loci other than MYCN.

Somatically acquired genomic alterations with MYCN amplification (MNA) are key features of neuroblastoma (NB), the most common extra-cranial malignant tumour of childhood. Little is known about the frequency, clinical characteristics and outcome of NBs harbouring genomic amplification(s) distinct fr...

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Bibliographic Details
Main Authors: Anne Guimier, Sandrine Ferrand, Gaëlle Pierron, Jérôme Couturier, Isabelle Janoueix-Lerosey, Valérie Combaret, Véronique Mosseri, Estelle Thebaud, Marion Gambart, Dominique Plantaz, Aurélien Marabelle, Carole Coze, Xavier Rialland, Sylvie Fasola, Eve Lapouble, Paul Fréneaux, Michel Peuchmaur, Jean Michon, Olivier Delattre, Gudrun Schleiermacher
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4094484?pdf=render

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http://europepmc.org/articles/PMC4094484?pdf=render

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