Validation of extracellular ligand–receptor interactions by Flow-TriCEPS

Validation of extracellular ligand–receptor interactions by Flow-TriCEPS

Abstract Objective The advent of ligand-based receptor capture methodologies, allows the identification of unknown receptor candidates for orphan extracellular ligands. However, further target validation can be tedious, laborious and time-consuming. Here, we present a methodology that provides a fas...

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Bibliographic Details
Main Authors: Laura A. Lopez-Garcia, Levent Demiray, Sandra Ruch-Marder, Ann-Katrin Hopp, Michael O. Hottiger, Paul M. Helbling, Maria P. Pavlou
Format: Article
Language:English
Published: BMC 2018-12-01
Series:BMC Research Notes
Subjects:
Flow-TriCEPS
HATRIC
LRC
Knock down
siRNA
Candidate verification
Online Access:http://link.springer.com/article/10.1186/s13104-018-3974-5

Internet

http://link.springer.com/article/10.1186/s13104-018-3974-5

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