Preferentially released miR-122 from cyclodextrin-based star copolymer nanoparticle enhances hepatoma chemotherapy by apoptosis induction and cytotoxics efflux inhibition

Chemotherapy, as one of the most commonly used treatment modalities for cancer therapy, provides limited benefits to hepatoma patients, owing to its inefficient delivery as well as the intrinsic chemo-resistance of hepatoma. Bioinformatic analysis identified the therapeutic role of a liver-specific...

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Bibliographic Details
Main Authors: Qingqing Xiong, Yang Bai, Run Shi, Jian Wang, Weiguo Xu, Mingming Zhang, Tianqiang Song
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2021-11-01
Series:Bioactive Materials
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X21001389