Targeting natural killer cell reactivity by employing antibody to NKp46: implications for type 1 diabetes.

Natural killer (NK) cells belong to the innate lymphoid cells. Their cytotoxic activity is regulated by the delicate balance between activating and inhibitory signals. NKp46 is a member of the primary activating receptors of NK cells. We previously reported that the NKp46 receptor is involved in the...

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Main Authors: Rami Yossef, Chamutal Gur, Avishai Shemesh, Ofer Guttman, Uzi Hadad, Shlomo Nedvetzki, Antonija Miletić, Karen Nalbandyan, Adelheid Cerwenka, Stipan Jonjic, Ofer Mandelboim, Angel Porgador
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4342013?pdf=render