Surface Acoustic Wave (SAW)-Enhanced Chemical Functionalization of Gold Films

Surface chemical and biochemical functionalization is a fundamental process that is widely applied in many fields to add new functions, features, or capabilities to a material’s surface. Here, we demonstrate that surface acoustic waves (SAWs) can enhance the chemical functionalization of gold films....

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Main Authors: Gina Greco, Matteo Agostini, Richie Shilton, Marco Travagliati, Giovanni Signore, Marco Cecchini
Format: Article
Language:English
Published: MDPI AG 2017-10-01
Series:Sensors
Subjects:
Online Access:https://www.mdpi.com/1424-8220/17/11/2452
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spelling doaj-07fbbabe48c946eab12acbdab5378db32020-11-25T01:12:09ZengMDPI AGSensors1424-82202017-10-011711245210.3390/s17112452s17112452Surface Acoustic Wave (SAW)-Enhanced Chemical Functionalization of Gold FilmsGina Greco0Matteo Agostini1Richie Shilton2Marco Travagliati3Giovanni Signore4Marco Cecchini5National Enterprise for nanoScience and nanoTechnology (NEST), Istituto Nanoscienze-CNR and Scuola Normale Superiore, Piazza San Silvestro 12, 56127 Pisa, ItalyNational Enterprise for nanoScience and nanoTechnology (NEST), Istituto Nanoscienze-CNR and Scuola Normale Superiore, Piazza San Silvestro 12, 56127 Pisa, ItalyCenter for Nanotechnology Innovation@NEST, Istituto Italiano di Tecnologia, Piazza San Silvestro 12, 56127 Pisa, ItalyNational Enterprise for nanoScience and nanoTechnology (NEST), Istituto Nanoscienze-CNR and Scuola Normale Superiore, Piazza San Silvestro 12, 56127 Pisa, ItalyNational Enterprise for nanoScience and nanoTechnology (NEST), Istituto Nanoscienze-CNR and Scuola Normale Superiore, Piazza San Silvestro 12, 56127 Pisa, ItalyNational Enterprise for nanoScience and nanoTechnology (NEST), Istituto Nanoscienze-CNR and Scuola Normale Superiore, Piazza San Silvestro 12, 56127 Pisa, ItalySurface chemical and biochemical functionalization is a fundamental process that is widely applied in many fields to add new functions, features, or capabilities to a material’s surface. Here, we demonstrate that surface acoustic waves (SAWs) can enhance the chemical functionalization of gold films. This is shown by using an integrated biochip composed by a microfluidic channel coupled to a surface plasmon resonance (SPR) readout system and by monitoring the adhesion of biotin-thiol on the gold SPR areas in different conditions. In the case of SAW-induced streaming, the functionalization efficiency is improved ≈ 5 times with respect to the case without SAWs. The technology here proposed can be easily applied to a wide variety of biological systems (e.g., proteins, nucleic acids) and devices (e.g., sensors, devices for cell cultures).https://www.mdpi.com/1424-8220/17/11/2452functionalizationmicrofluidicssurface acoustic waves (SAWs)
collection DOAJ
language English
format Article
sources DOAJ
author Gina Greco
Matteo Agostini
Richie Shilton
Marco Travagliati
Giovanni Signore
Marco Cecchini
spellingShingle Gina Greco
Matteo Agostini
Richie Shilton
Marco Travagliati
Giovanni Signore
Marco Cecchini
Surface Acoustic Wave (SAW)-Enhanced Chemical Functionalization of Gold Films
Sensors
functionalization
microfluidics
surface acoustic waves (SAWs)
author_facet Gina Greco
Matteo Agostini
Richie Shilton
Marco Travagliati
Giovanni Signore
Marco Cecchini
author_sort Gina Greco
title Surface Acoustic Wave (SAW)-Enhanced Chemical Functionalization of Gold Films
title_short Surface Acoustic Wave (SAW)-Enhanced Chemical Functionalization of Gold Films
title_full Surface Acoustic Wave (SAW)-Enhanced Chemical Functionalization of Gold Films
title_fullStr Surface Acoustic Wave (SAW)-Enhanced Chemical Functionalization of Gold Films
title_full_unstemmed Surface Acoustic Wave (SAW)-Enhanced Chemical Functionalization of Gold Films
title_sort surface acoustic wave (saw)-enhanced chemical functionalization of gold films
publisher MDPI AG
series Sensors
issn 1424-8220
publishDate 2017-10-01
description Surface chemical and biochemical functionalization is a fundamental process that is widely applied in many fields to add new functions, features, or capabilities to a material’s surface. Here, we demonstrate that surface acoustic waves (SAWs) can enhance the chemical functionalization of gold films. This is shown by using an integrated biochip composed by a microfluidic channel coupled to a surface plasmon resonance (SPR) readout system and by monitoring the adhesion of biotin-thiol on the gold SPR areas in different conditions. In the case of SAW-induced streaming, the functionalization efficiency is improved ≈ 5 times with respect to the case without SAWs. The technology here proposed can be easily applied to a wide variety of biological systems (e.g., proteins, nucleic acids) and devices (e.g., sensors, devices for cell cultures).
topic functionalization
microfluidics
surface acoustic waves (SAWs)
url https://www.mdpi.com/1424-8220/17/11/2452
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AT marcotravagliati surfaceacousticwavesawenhancedchemicalfunctionalizationofgoldfilms
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AT marcocecchini surfaceacousticwavesawenhancedchemicalfunctionalizationofgoldfilms
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