H3K36 Methylation Regulates Nutrient Stress Response in Saccharomyces cerevisiae by Enforcing Transcriptional Fidelity

Set2-mediated histone methylation at H3K36 regulates diverse activities, including DNA repair, mRNA splicing, and suppression of inappropriate (cryptic) transcription. Although failure of Set2 to suppress cryptic transcription has been linked to decreased lifespan, the extent to which cryptic transc...

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Bibliographic Details
Main Authors: Stephen L. McDaniel, Austin J. Hepperla, Jie Huang, Raghuvar Dronamraju, Alexander T. Adams, Vidyadhar G. Kulkarni, Ian J. Davis, Brian D. Strahl
Format: Article
Language:English
Published: Elsevier 2017-06-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717307143